Traitement par la dapsone des formes cutanées chroniques du purpura rhumatoïde : à propos de 3 cas

Mazille, N.; Lipsker, Dan; Fischbach, Michel

doi:10.1016/j.arcped.2011.08.011

Cited by 9 publications

(2 citation statements)

References 10 publications

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“…In 3 other cases, dapsone was initiated as treatment for chronic, recurrent, persisting purpuric skin lesions. The outcome was complete healing in all cases (51).…”

Section: Other Immunosuppressive and Immunomodulatory Treatmentmentioning

confidence: 84%

Henoch-Schönlein Purpura: A Literature Review

Hetland¹,

Susrud²,

Lindahl³

et al. 2017

Acta Derm Venerol

193

164

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Henoch-Schönlein purpura is the most common childhood vasculitis, but may also affect adults. This article reviews the literature since 2011 on advances in diagnosis, clinical disease manifestations, pathophysiology and treatment of Henoch-Schönlein purpura. The clinical manifestations are thought to arise from IgA depositions in blood vessel walls in the affected organs, mostly skin, gastrointestinal tract, joints and kidneys. Corticosteroids may be effective in rapid resolution of renal manifestations and treating joint and abdominal pain, but they are not proven effective for treating organ manifestations and complications, such as glomerulonephritis, bowel infarction or intussusception. Mycophenolate mofetil or cyclosporine A may be better treatment choices in case of renal involvement. Other immunosuppressive and immunomodulating drugs, such as rituximab and dapsone, are promising, but larger studies are needed to confirm these findings. Cancer screening should be considered in older males diagnosed with Henoch-Schönlein purpura.

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“…In 3 other cases, dapsone was initiated as treatment for chronic, recurrent, persisting purpuric skin lesions. The outcome was complete healing in all cases (51).…”

Section: Other Immunosuppressive and Immunomodulatory Treatmentmentioning

confidence: 84%

Henoch-Schönlein Purpura: A Literature Review

Hetland¹,

Susrud²,

Lindahl³

et al. 2017

Acta Derm Venerol

193

164

View full text Add to dashboard Cite

show abstract

“…Corticosteroids might reduce the severity and duration of gastrointestinal symptoms, but no benefit has been demonstrated for the incidence of nephropathy [3]. Recurrent or chronic pediatric HSP successfully treated with dapsone has been occasionally reported but with prompt relapse after tapering and side effects such as methemoglobinemia [4]. Nonsteroidal anti-inflammatory drugs are effective for arthritis and arthralgia, but their effectiveness in cutaneous manifestations of HSP has not been reported.…”

Section: Introductionmentioning

confidence: 96%