Tranexamic acid derived gold nanoparticles modified glassy carbon electrode as sensitive sensor for determination of nalbuphine

Shaikh, Tayyaba; Nafady, Ayman; Talpur, Farah Naz; Sirajuddin, Sirajuddin; Agheem, Muhammad Hassan; Shah, Muhammad Raza; Sherazi, Syed Tufail Hussain; Soomro, Razium Ali; Siddiqui, Samia

doi:10.1016/j.snb.2015.01.096

Cited by 46 publications

(26 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The amperometric curves at different concentration ranges of nitrite are depicted as overlapped curves in Figure . Upon each addition of nitrite with sample interval of 30 s, an enhancement in current response was observed and steady state value was achieved within 20 s. The current responses were found to depend linearly with the nitrite concentration at the ranges of 0.5 µM to 7.5 µM and 5 µM to 480 µM.The limit of detection was found by taking three times standard deviation of blank and dividing the resultant value by slope of the calibration plot as reported in our earlier studies . The calculated detection limits from corresponding calibration plots have been shown in Table .…”

Section: Resultsmentioning

confidence: 83%

See 1 more Smart Citation

Selective and Sensitive Nitrite Sensor Based on Glassy Carbon Electrode Modified by Silver Nanochains

et al. 2016

Self Cite

View full text Add to dashboard Cite

Herein, we report a facile method for the synthesis of silver nanochains (Ag nanochains) using pyridine as growth directing agent and citrate ions as capping agents in alkaline medium. The characterization of the synthesized high aspect ratio Ag nanochains was accomplished with the help of Transmission Electron Microscopy (TEM) and High Resolution Transmission Electron Microscopy (HRTEM) which demonstrates the thickness below 100 nm. Crystalline nature of the synthesized Ag nanochains was investigated using X‐ray diffractrometry. A sensitive electrochemical nitrite sensor was assembled using synthesized Ag nanochains as electrode modifier. An improved cyclic voltammetric response for the oxidation of nitrite ions was witnessed at the modified GCE surface in comparison to bare GCE in Britton Robinson (BR) buffer (pH 4). The influence of pH on the oxidation peak current of nitrite ions was also examined using cyclic voltammetry. The electrocatalytic oxidation currents attained through amperometric measurements at Ag nanochains modified GCE were linearly dependent on the concentration of nitrite ions in the two ranges of 0.5–7.5 µM, 5–480 µM. Linear calibration plots of Ip vs. concentration of nitrite were also constructed at the proposed sensor using square wave voltammetry and differential pulse voltammetry. The proposed sensing strategy was successfully employed for the determination of nitrite in water samples with excellent recoveries.

show abstract

Section: Resultsmentioning

confidence: 83%

“…The electrocatalytic nature can be attributed to the chain like structure of the fabricated Ag nanochains that motives facile electron transfer at the electrode surface. Additionally, the presence of Nafion (1 %) imparts stability to the electrode by preventing the escape of Ag nanochains from electrode surface into the solution .…”

Section: Resultsmentioning

confidence: 99%

Selective and Sensitive Nitrite Sensor Based on Glassy Carbon Electrode Modified by Silver Nanochains

et al. 2016

Self Cite

View full text Add to dashboard Cite

show abstract

“…The corresponding inset plot shows an R 2 value of 0.9951 with LOD of 12 nM and LOQ of 40 nM. The LOD and LOQ values were determined by the methods reported previously [9,24]. Although the electrode was checked for 100-3600 nM nitrite concentration and was giving good results but the former range was producing the higher linearity and thus chosen for better accuracy.…”

Section: Amperometric Calibrationmentioning

confidence: 99%

“…Among these, the electroanalytical methods are considered more efficient due to lower cost, portable instruments, simpler set-up, ease of sample preparation and processing, and higher sensitivity/selectivity [9,10]. These characteristics make electroanalysis the method of choice for many diagnostic studies.…”

Section: Introductionmentioning

confidence: 99%

Construction of an Ultrasensitive and Highly Selective Nitrite Sensor Using Piroxicam-Derived Copper Oxide Nanostructures

et al. 2018

Self Cite

View full text Add to dashboard Cite

Abstract:In this work, piroxicam-based copper oxide nanostructures (Px-CuO NSs) were synthesized via hydrothermal precipitation in the presence of ammonia. The prepared Px-CuO NSs were subjected to scanning electron microscopy (SEM) and X-ray diffraction (XRD) to obtain morphology and crystallinity, respectively. The SEM study reveals that these Px-CuO NSs are in the form of porous rose-like nanopetals with dotted particles on their surface, while the XRD study confirms their crystalline nature. The Px-CuO NS-based sensors were fabricated by drop-casting them onto the surface of a glassy carbon electrode (GCE) and they were tested for nitrite detection using voltammetry and amperometry. The results show these Px-CuO NSs to be highly stable on the GCE surface with linear amperometric (current vs. time) responses to wide range of nitrite concentrations from 100 to 1800 nM, with limits of detection (LOD) and quantification (LOQ) being 12 nM and 40 nM, respectively. Importantly, the fabricated sensor showed negligible effects for a 10-fold higher concentration of common interfering agents and exhibited excellent selectivity. It was applied successfully for nitrite detection in water samples such as river water, mineral water, and tap water.

show abstract

“…NP⋅HCl was simultaneously determined in human hair by gas chromatography, mass spectrometry [10]. Tranexamic acid derived gold nanoparticles modified glassy carbon electrode was used as a sensor for NP determination where the sensor responded linearly in the range of 0.05-1.25 g mL −1 [11]. NP⋅HCl was determined spectrophotometrically using N-bromosuccinimide as an oxidant [12] and stability indicating methods [13].…”

Section: Introductionmentioning

confidence: 99%

Utility of Activated Glassy Carbon and Pencil Graphite Electrodes for Voltammetric Determination of Nalbuphine Hydrochloride in Pharmaceutical and Biological Fluids

Elqudaby

Hendawy

Souaya

et al. 2016

International Journal of Electrochemistry

View full text Add to dashboard Cite

This work compares voltammetric response of nalbuphine hydrochloride (NP⋅HCl) at both activated glassy carbon and pencil graphite electrodes. The electrochemical oxidation of the drug was studied using cyclic voltammetry (CV), differential pulse voltammetry (DPV), and square wave voltammetry (SWV) techniques. For analytical purpose a well-resolved irreversible diffusion controlled voltammetric peak was established in Britton-Robinson (B-R) buffer solution of pH 6.00 using pencil graphite electrode (PGE). Using activated glassy carbon electrode (GCE) a well-resolved irreversible diffusion controlled voltammetric peak was obtained at pH 7.00 using the same buffer solution. According to the linear relationship between the peak current and NP⋅HCl concentration, DPV and SWV methods were developed for their quantitative determination in pharmaceutical and human biological fluids. The linear response was obtained in the range from 1.6×10 −5 to 1.5×10 −4 mol L −1 using PGE and from 12.5×10 −6 to 13.75 × 10 −5 mol L −1 using a GC electrode, respectively. Precision and accuracy of the developed method were checked by recovery studies.

show abstract

Tranexamic acid derived gold nanoparticles modified glassy carbon electrode as sensitive sensor for determination of nalbuphine

Cited by 46 publications

References 36 publications

Selective and Sensitive Nitrite Sensor Based on Glassy Carbon Electrode Modified by Silver Nanochains

Selective and Sensitive Nitrite Sensor Based on Glassy Carbon Electrode Modified by Silver Nanochains

Construction of an Ultrasensitive and Highly Selective Nitrite Sensor Using Piroxicam-Derived Copper Oxide Nanostructures

Utility of Activated Glassy Carbon and Pencil Graphite Electrodes for Voltammetric Determination of Nalbuphine Hydrochloride in Pharmaceutical and Biological Fluids

Contact Info

Product

Resources

About