Transabdominal electrical stimulation (TES) for the treatment of slow-transit constipation (STC)

Hutson, John M.; Dughetti, L.; Stathopoulos, Lefteris; Southwell, Bridget R.

doi:10.1007/s00383-015-3681-4

Cited by 30 publications

(27 citation statements)

References 66 publications

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“…These children had an increase in the frequency of antegrade propagating contractions with manometric patterns improving to lie in the normal range. 13,33 Nuclear transit studies in some of these same children showed an improvement in transit time. However, those with concurrent upper gastrointestinal dysmotility did not respond as well to interferential current therapy compared with those participants with slow transit colon and normal upper gastrointestinal motility.…”

Section: Studies In Childrenmentioning

confidence: 83%

“…It has the benefit of being completely non-invasive, cost effective and convenient, as it can be self-administered at home. 13 Despite increased convenience to the patient, doctor and payer, the use of transcutaneously-delivered current can be problematic. To stimulate the nerve of interest, the current has to pass through the skin and surrounding muscle to reach its target.…”

Section: The Nature Of Interferential Current Therapymentioning

confidence: 99%

“…13 Chronic constipation remains a difficult condition to treat and children refractory to traditional treatments face surgical procedures such as appendicostomy or colectomy.…”

Section: Studies In Childrenmentioning

confidence: 99%

“…1). 13 Participants received between 9 and 12 stimulation sessions over a 4-week period. 9 Soiling disappeared in the first 2 weeks after interferential current therapy in 6 of the 7, although long-term effects were less impressive.…”

Section: Studies In Childrenmentioning

confidence: 99%

“…19 In this study, their leads were all on the one plane, which contrasts to previous reports of the transabdominal approach where 2 electrodes are on the abdomen and 2 on the back, and the currents cross diagonally through the abdomen. 9,13 This may have affected the outcomes. As the results were presented as the number of patients who reported improvement, not as individual scores, the overall effect size is not clear.…”

Section: Studies In Adultsmentioning

confidence: 99%

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Neuromodulation via Interferential Electrical Stimulation as a Novel Therapy in Gastrointestinal Motility Disorders

Moore

Burgell

2018

J Neurogastroenterol Motil

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The concept of therapeutic percutaneous neuromodulation has, until recently, been limited by the ability to penetrate deeply enough to stimulate internal organs. By utilizing 2 medium frequency, slightly out of phase electrical currents passing diagonally through the abdomen, a third, low frequency current is created at the point of bisection. This interferential current appears to stimulate nerve fibers in the target organs and may have a therapeutic action. The aim of the study is to review the use of transcutaneous interferential electrical stimulation with a focus on its application in gastroenterology, particularly in motility disorders. Studies involving use of interferential current therapy were searched from Medline, PubMed, and Scopus databases, and articles pertaining to history, its application and all those treating abdominal and gastrointestinal disorders were retrieved. Seventeen studies were identified, 13 involved children only. Eleven of these were randomised controlled trials (3 in adults). Four trials were from the one center, where each paper reported on different outcomes such as soiling, defecation frequency, quality of life, and colon transit studies from the one pool of children. All studies found statistically significant improvement in symptom reduction. However, weaknesses in study design were apparent in some. In particular, finding an adequate placebo to interferential current therapy has been difficult. Interferential current therapy shows potential as a novel, non-pharmacological and economical means of treating gastrointestinal dysfunction such as constipation. More studies are needed particularly in the adult population. However, the design of a suitable placebo is challenging. Search MethodA search of Medline, PubMed, and Scopus databases for information on electrical interferential current and its application using search words such as "electrical interferential current," "transcutaneous," "therapeutics or uses," "mechanisms of action," and "gastrointestinal" was performed. Articles that were available in English were included. This review focuses on the use of transcutaneous interferential current therapy in the treatment of gastrointestinal symptoms. The Nature of Interferential Current TherapyInterferential current therapy has been used in a variety of settings including low back pain 11 and neurological disorders such as carpal tunnel syndrome. 12 More recently, interferential current therapy has been found to be effective in small studies in managing conditions such as fecal incontinence and constipation. It has the benefit of being completely non-invasive, cost effective and convenient, as it can be self-administered at home. 13Despite increased convenience to the patient, doctor and payer, the use of transcutaneously-delivered current can be problematic. To stimulate the nerve of interest, the current has to pass through the skin and surrounding muscle to reach its target. This causes resistance to flow, requiring the use of a higher current to achieve the desired resu...

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Section: Studies In Childrenmentioning

confidence: 83%

Section: The Nature Of Interferential Current Therapymentioning

confidence: 99%

“…13 Chronic constipation remains a difficult condition to treat and children refractory to traditional treatments face surgical procedures such as appendicostomy or colectomy.…”

Section: Studies In Childrenmentioning

confidence: 99%

Section: Studies In Childrenmentioning

confidence: 99%

Section: Studies In Adultsmentioning

confidence: 99%

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Neuromodulation via Interferential Electrical Stimulation as a Novel Therapy in Gastrointestinal Motility Disorders

Moore

Burgell

2018

J Neurogastroenterol Motil

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Long-term outcome after segmental colonic resection for slow transit constipation

Tsimogiannis

Karlbom

Lundin

et al. 2019

Int J Colorectal Dis

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Purpose Colectomy with ileorectal anastomosis (IRA) is the most common surgical procedure for slow transit constipation (STC). A hemicolectomy has been suggested as an alternative to IRA with good short-term results. However, long-term results are unknown. The aim of this study was to evaluate the long-term results after hemicolectomy as a treatment for STC. Methods Fifty patients with STC were selected for right-or left-sided hemicolectomy after evaluation with colonic scintigraphy from 1993 to 2008. Living patients (n = 43) received a bowel function questionnaire and a questionnaire about patient-reported outcome. Results After a median follow-up of 19.8 years, 13 patients had undergone rescue surgery (n = 12) or used irrigation (n = 1) and were classified as failures. In all, 30 were evaluable for functional outcome and questionnaire data for 19 patients (due to 11 nonresponding) could be analysed. Two reported deterioration after several years and were also classified as failures. Median stool frequency remained increased from 1 per week at baseline to 5 per week at long-term follow-up (p = 0.001). Preoperatively, all patients used laxatives, whereas 12 managed without laxatives at long-term follow-up (p = 0.002). There was some reduction in other constipation symptoms but not statically significant. In the patients' global assessment, 10 stated a very good result, seven a good result and two a poor result. Conclusions Hemicolectomy for STC increases stool frequency and reduces laxative use. Long-term success rate could range between 17/50 (34%) and 35/50 (70%) depending on outcome among non-responders.

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The Sphincter of O’Beirne—Part 2: Report of a Case of Chronic Constipation with Autonomous Dyssynergia

et al. 2021

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Transabdominal electrical stimulation (TES) for the treatment of slow-transit constipation (STC)

Cited by 30 publications

References 66 publications

Neuromodulation via Interferential Electrical Stimulation as a Novel Therapy in Gastrointestinal Motility Disorders

Neuromodulation via Interferential Electrical Stimulation as a Novel Therapy in Gastrointestinal Motility Disorders

Long-term outcome after segmental colonic resection for slow transit constipation

The Sphincter of O’Beirne—Part 2: Report of a Case of Chronic Constipation with Autonomous Dyssynergia

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