“…Since that time, endoscopic thyroidectomy (ET) has been used throughout the planet via multiple approaches, anterior chest, axillary fossa, breast, retroauricular, and combined. [3][4][5][6][7] Although ET has been favorably reviewed, 8,9 it has not been fully accepted and is still limited to some high volume centers. 10 The use of the endoscope for thyroidectomy is dissimilar to its use in other procedures: (1) unlike, for example, cholecystectomy, ET is a cosmetic, not a minimally invasive procedure 11 ; (2) the suitability of ET for thyroid carcinoma has yet to be determined, an issue given potential transplantation of cancers cells via the ''the chimney effect of CO 2 '' 12 ; and (3) technical difficulties 6,[8][9][10][11] (e.g., identification of thyroid neoplasm under endoscope, working space requirements, and instrumentation) hindered ET's acceptance.…”