Transcription factor WOX11 modulates tolerance to cyst nematodes via adventitious lateral root formation

Willig, Jaap-Jan; Guarneri, Nina; van Loon, Thomas; Wahyuni, Sri; Astudillo-Estévez, Ivan E; Xu, Lin; Willemsen, Viola; Goverse, Aska; Sterken, Mark G; Lozano-Torres, José L; Bakker, Jaap; Smant, Geert

doi:10.1093/plphys/kiae053

Cited by 3 publications

(1 citation statement)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A role for LBD16 in feeding site formation induced by CNs has not been described. However, LBD16 is induced in a WOX11-dependent manner in the primordia of adventitious lateral roots that are promoted after H. schchatii infection ( Willig et al., 2024 ). This finding connects the plant-responses to both, RKNs and CNs, to the activation of critical transducers of root developmental programs.…”

Section: Plant Transcription Factors Relevant During Rkns Infection W...mentioning

confidence: 99%

Functional studies of plant transcription factors and their relevance in the plant root-knot nematode interaction

Domínguez-Figueroa,

Gómez-Rojas,

Escobar

2024

Front. Plant Sci.

View full text Add to dashboard Cite

Root-knot nematodes are polyphagous parasitic nematodes that cause severe losses in the agriculture worldwide. They enter the root in the elongation zone and subtly migrate to the root meristem where they reach the vascular cylinder and establish a feeding site called gall. Inside the galls they induce a group of transfer cells that serve to nurture them along their parasitic stage, the giant cells. Galls and giant cells develop through a process of post-embryogenic organogenesis that involves manipulating different genetic regulatory networks within the cells, some of them through hijacking some molecular transducers of established plant developmental processes, such as lateral root formation or root regeneration. Galls/giant cells formation involves different mechanisms orchestrated by the nematode´s effectors that generate diverse plant responses in different plant tissues, some of them include sophisticated mechanisms to overcome plant defenses. Yet, the plant-nematode interaction is normally accompanied to dramatic transcriptomic changes within the galls and giant cells. It is therefore expected a key regulatory role of plant-transcription factors, coordinating both, the new organogenesis process induced by the RKNs and the plant response against the nematode. Knowing the role of plant-transcription factors participating in this process becomes essential for a clear understanding of the plant-RKNs interaction and provides an opportunity for the future development and design of directed control strategies. In this review, we present the existing knowledge of the TFs with a functional role in the plant-RKN interaction through a comprehensive analysis of current scientific literature and available transcriptomic data.

show abstract

Section: Plant Transcription Factors Relevant During Rkns Infection W...mentioning

confidence: 99%

Functional studies of plant transcription factors and their relevance in the plant root-knot nematode interaction

Domínguez-Figueroa,

Gómez-Rojas,

Escobar

2024

Front. Plant Sci.

View full text Add to dashboard Cite

show abstract

WOX11‐mediated cell size control in Arabidopsis attenuates growth and fecundity of endoparasitic cyst nematodes

Guarneri,

Willig,

Willemsen

et al. 2024

The Plant Journal

View full text Add to dashboard Cite

SUMMARYCyst nematodes establish permanent feeding structures called syncytia inside the host root vasculature, disrupting the flow of water and minerals. In response, plants form WOX11‐mediated adventitious lateral roots at nematode infection sites. WOX11 adventitious lateral rooting modulates tolerance to nematode infections; however, whether this also benefits nematode parasitism remains unknown. Here, we report on bioassays using a 35S::WOX11‐SRDX transcriptional repressor mutant to investigate whether WOX11 adventitious lateral rooting promotes syncytium development and thereby female growth and fecundity. Moreover, we chemically inhibited cellulose biosynthesis to verify if WOX11 directly modulates cell wall plasticity in syncytia. Finally, we performed histochemical analyses to test if WOX11 mediates syncytial cell wall plasticity via reactive oxygen species (ROS). Repression of WOX11‐mediated transcription specifically enhanced the radial expansion of syncytial elements, increasing both syncytium size and female offspring. The enhanced syncytial hypertrophy observed in the 35S::WOX11‐SRDX mutant could be phenocopied by chemical inhibition of cellulose biosynthesis and was associated with elevated levels of ROS at nematode infection sites. We, therefore, conclude that WOX11 restricts radial expansion of nematode‐feeding structures and female growth and fecundity, likely by modulating ROS‐mediated cell wall plasticity mechanisms. Remarkably, this novel role of WOX11 in plant cell size control is distinct from WOX11 adventitious lateral rooting underlying disease tolerance.

show abstract

Biochemical Defence of Plants against Parasitic Nematodes

Meresa,

Matthys,

Kyndt

2024

Plants

View full text Add to dashboard Cite

Plant parasitic nematodes (PPNs), such as Meloidogyne spp., Heterodera spp. and Pratylenchus spp., are obligate parasites on a wide range of crops, causing significant agricultural production losses worldwide. These PPNs mainly feed on and within roots, impairing both the below-ground and the above-ground parts, resulting in reduced plant performance. Plants have developed a multi-component defence mechanism against diverse pathogens, including PPNs. Several natural molecules, ranging from cell wall components to secondary metabolites, have been found to protect plants from PPN attack by conferring nematode-specific resistance. Recent advances in omics analytical tools have encouraged researchers to shed light on nematode detection and the biochemical defence mechanisms of plants during nematode infection. Here, we discuss the recent progress on revealing the nematode-associated molecular patterns (NAMPs) and their receptors in plants. The biochemical defence responses of plants, comprising cell wall reinforcement; reactive oxygen species burst; receptor-like cytoplasmic kinases; mitogen-activated protein kinases; antioxidant activities; phytohormone biosynthesis and signalling; transcription factor activation; and the production of anti-PPN phytochemicals are also described. Finally, we also examine the role of epigenetics in regulating the transcriptional response to nematode attack. Understanding the plant defence mechanism against PPN attack is of paramount importance in developing new, effective and sustainable control strategies.

show abstract

Transcription factor WOX11 modulates tolerance to cyst nematodes via adventitious lateral root formation

Cited by 3 publications

References 35 publications

Functional studies of plant transcription factors and their relevance in the plant root-knot nematode interaction

Functional studies of plant transcription factors and their relevance in the plant root-knot nematode interaction

WOX11‐mediated cell size control in Arabidopsis attenuates growth and fecundity of endoparasitic cyst nematodes

Biochemical Defence of Plants against Parasitic Nematodes

Contact Info

Product

Resources

About