Transcriptome analyses profiles of dietary l‐alanyl‐l‐glutamine supplementation in Amur sturgeon, Acipenser schrenckii, liver

Abstract

To investigate the effect of dietary L-Alanyl-L-glutamine (Ala-Gln) supplementation on Amur sturgeon, Acipenser schrenckii, 180 healthy fish (initial body weight 21.23 ± 0.17 g) were divided into two groups (30 fish per tank, each treatment in triplicate) and treated with 0.0% (control) and 1.0% Ala-Gln for 56 days. The growth performance improved significantly with dietary Ala-Gln supplementation. Transcriptome profiles of dietary Ala-Gln supplementation in sturgeon were generated using second-generation Illumina sequencing technology. A total of 2891 differentially expressed genes (DEGs) were obtained, including 901, which were upregulated, and 1990, which were downregulated, in the treatment group relative to the control group. These genes are mainly involved in the general function, regulation of replication, recombination and repair, signal transduction mechanisms, amino acids and lipid transport