Abstract:Atrial fibrillation (AF), the most common arrhythmia with an overall prevalence of 0.51%, is associated with increased morbidity and mortality, as well as important healthcare costs. AF develops over many years and is often associated with substantial changes in the structural and electrophysiological properties of the atria. Because AF may lack subclinical symptoms at onset, it has been difficult to study the molecular and cellular events associated with earlier stages of this pathology in humans. Here, we ch… Show more
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