2009
DOI: 10.1182/blood.v114.22.3157.3157
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Transfusion Associated Circulatory Overload (TACO) Incidence and Risk Factors.

Abstract: 3157 Poster Board III-94 Introduction Transfusion circulatory overload (TACO) is a complication of transfusion, often confused with transfusion acute lung injury (TRALI), and is probably under-reported. The pathophysiology is believed to be caused by increased hydrostatic blood pressure leading to fluid leakage in the alveolar space, emulating congestive cardiac failure. We report on a large cohort of TACO cases in Ireland. … Show more

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Cited by 9 publications
(17 citation statements)
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“…Pretransfusion diuretic therapy was not found to be protective. This is similar to the findings of Andrea et al 21 . where 40% of patients received diuretics but still progressed to TACO.…”
Section: Discussionsupporting
confidence: 92%
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“…Pretransfusion diuretic therapy was not found to be protective. This is similar to the findings of Andrea et al 21 . where 40% of patients received diuretics but still progressed to TACO.…”
Section: Discussionsupporting
confidence: 92%
“…Our previous study noted a higher rate of TACO (1 in 356) than TRALI (1 in 534) per unit of blood component transfused 3 . This is much higher than the incidence rate in a recent hemovigilance report from Ireland (1/10,000 of all components) 21 . In addition to a different study population (critically ill patients vs. all transfused patients), the major difference is likely a result of different identification methods (prospective observation vs. passive reporting).…”
Section: Discussionmentioning
confidence: 67%
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“…Transfusion-associated circulatory overload (TACO) is the most common type of transfusion-related pulmonary complication with an estimated incidence estimate of 1–8% (although some estimating it to be as high as 11%) [ 11 ]. TACO was first observed in the 1930s, but became recognized as a distinct clinical entity in the 1990s [ 12 ]. The incidence of TACO varies by study, with data from passive surveillance showing a very low incidence while studies with active surveillance reporting a higher incidence.…”
Section: Transfusion-associated Circulatory Overloadmentioning
confidence: 99%