Transient Accommodative Paresis Complicating Mumps

Morrison, Frank D.

doi:10.1001/archopht.1965.00970030088018

Cited by 2 publications

(1 citation statement)

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“…9 Few cases exist of ocular muscle palsies associated with systemic mumps infection. 4,5,10,11 However, to the best of our knowledge, we found no reports on painful ophthalmoplegia in the literature.…”

Section: Discussionmentioning

confidence: 85%

A Case of Idiopathic Orbital Inflammation With Elevated Anti-Mumps Immunoglobulin M Antibody

Han,

Woo

2024

Ophthalmic Plastic &Amp; Reconstructive Surgery

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A 21-year-old female presented with periocular swelling, diplopia, and painful ophthalmoplegia in the OS. Orbital magnetic resonance imaging revealed an enhanced soft tissue mass involving the left medial rectus muscle. Laboratory test results revealed leukocytosis, elevated reactive C-reactive protein, and positive serum levels of anti-mumps immunoglobulin M (IgM) antibody without systemic manifestations of mumps infection. The clinical course was refractory, and the patient showed a poor response to high-dose steroids. An incisional biopsy revealed stromal fibrosis with focal lymphoid aggregates, indicating sclerosing inflammation. Myopathy of the medial rectus progressed to superior, inferior, and lateral recti involvement of the left orbit. Immunosuppressive agents, including steroids, were administered for 22 months after disease onset. The mumps IgM antibody level was positive for over 5 months and became negative upon testing performed 1 year after the first visit.

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