Transient Aquagenic Palmar Hyperwrinkling

Atypical familial aquagenic syringeal acrokeratoderma

“…Typical histologic findings of water‐exposed lesions in ASA include orthohyperkeratosis, dilated sweat duct ostia (which can be visualized with dermoscopy), 5,7,8,10,13 dilated eccrine ducts, hypergranulosis, acanthosis, hyperplasia of eccrine glands with clear‐cell change and vacuolation, and increased capillaries around eccrine coils 14 . We identified 134 cases of ASA reported in the literature and we summarize the commonly reported microscopic findings in Table 1 2‐11,14‐91 …”