Transient bone marrow lymphoproliferation after umbilical cord blood transplantation: Exacerbated reconstitution of B‐cell ontogeny in adults

Jerez, Andrés; Osma, Maria del Mar; Castilla‐Llorente, Cristina; Bernal, Agustina; Palacios, S.; Heras, Inmaculada; Ortuño, Francisco José

doi:10.1002/ajh.22013

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“…5 Furthermore, heterogeneous B-cell lymphoproliferation, with complex morphological and phenotypical features, has been recently described in patients with AML after allo-cord blood SCT. 6 Direct observation of BM smear and flow cytometry are the two fastest techniques for the detection of relapse after therapy in patients with leukemia. Moreover, persistence of minimal residual disease measured by flow cytometry after SCT has been associated with lower disease-free survival in ALL patients.…”

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confidence: 99%