Transient complete atrioventricular block associated with curcumin intake

Lee, Se-Whan; Nah, Seong‐Su; Byon, Jin-Soo; Ko, Hee Ja; Park, Sang-Ho; Lee, Seung-Jin; Shin, Won-Yong; Jin, Dong‐Kyu

doi:10.1016/j.ijcard.2009.09.530

Cited by 15 publications

(8 citation statements)

References 9 publications

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“…However, when large doses are employed there might be some side-effects associated with its use. In a case report, it has been reported that high dose of oral supplementary turmeric/curcumin was associated with atrioventricular block, which disappeared after cessation of the turmeric/curcumin containing pills and reappeared by re-intake of the same amount of the same pills (36). Also, turmeric/ curcumin may raise the risk of bleeding by increasing the effects of anticoagulant drugs, such as warfarin (Coumadin), clopidogrel (Plavix), and aspirin, and, it is advisable to avoid supplementary turmeric/curcumin in patients on such drugs (37).…”

Section: Resultsmentioning

confidence: 99%

Turmeric: Reemerging of a Neglected Asian Traditional Remedy

Khajehdehi¹

2012

jnp

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Section: Resultsmentioning

confidence: 99%

Turmeric: Reemerging of a Neglected Asian Traditional Remedy

Khajehdehi¹

2012

jnp

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“…Withdrawal of the causative medication and adequate supportive care can lead to a favorable outcome in these patients. [ 20 ] In certain critical cases, extracorporeal membrane oxygenation can be helpful when conventional treatments are not effective. [ 21 ]…”

Section: Discussionmentioning

confidence: 99%

Transient sick sinus syndrome with complete atrioventricular block associated with ergonovine intake

Wang

Liu²,

Chen³

2017

Medicine

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Rationale:More mature or older women are more likely to undergo in vitro fertilization and embryo implant. These women have a greater chance of receiving ergonovine therapy because of a suspected abortion. We present this case report to call attention to a latent lethal adverse effect in everyday obstetric practice using ergonovine. It requires more attention and close monitoringPatient concerns:We presented the case of a 38-year-old female patient with general weakness and mild chest tightness after ergonovine use.Diagnoses:She was diagnosed as transient sick sinus syndrome and complete atrioventricular block with junctional escape rhythm after diagnostic work up.Interventions:Conservative treatment with discontinuation of ergonovine and bed rest.Outcomes:Her sinus rhythm returned to normal the day after ergonovine was discontinued. The patient remained symptom-free since recovery of her sinus rhythm.Lessons:Ergonovine may cause symptomatic and lethal bradyarrhythmia. Withdrawal of the causative medication and adequate supportive care can lead to a favorable outcome in these patients. More related cases should be reported. Further evaluation for treatment and prognosis are necessary.

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“…77 Interestingly, transient complete heart block was reported in a male after intake of curcumin-containing pills for one month and no further conduction disturbances were noticed on cessation of the pills. 78 Ginger Ginger (Zingiber officinale) has been used since time immemorial as a home remedy for many ailments. It has an effect on diuresis, heart rate (through channelopathy), and blood pressure.…”

Section: Turmericmentioning

confidence: 99%