Transient complete heart block in a patient with critical COVID-19

Azarkish, Mona; Far, Vahideh Laleh; Eslami, Masoud; Mollazadeh, Reza

doi:10.1093/eurheartj/ehaa307

Cited by 78 publications

(79 citation statements)

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“…Sudden onset complete heart block occurred in one of the 32 patients (3.1%), which was transient and disappeared after atropine injection and CPR. This was the first report of atrioventricular block in the COVID-19 [7]. It could be due atrioventricular involvement in the context of myocarditis by coronavirus, drug induced (lopinavir/ritonavir) , hypoxia or central autonomic dysfunction and parasympathetic activation in the medulla [2].…”

Section: Discussionmentioning

confidence: 79%

Electrocardiographic Holter monitoring findings in critical coronavirus disease-19 patients

Far¹,

Mehrakizadeh²,

Eslami³

et al. 2020

Polish Archives of Internal Medicine

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This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (CC BY-NC-SA 4.0), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited, distributed under the same license, and used for noncommercial purposes only.

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Section: Discussionmentioning

confidence: 79%

Electrocardiographic Holter monitoring findings in critical coronavirus disease-19 patients

Far¹,

Mehrakizadeh²,

Eslami³

et al. 2020

Polish Archives of Internal Medicine

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“…Debe remarcarse que el curso de la enfermedad fue más acelerado ante la presencia de lesión cardíaca. Asimismo, se han reportado a la fecha casos de miocarditis, tako-tsubo y bloqueo auriculoventricular en relación con la COVID-19 [12][13][14] (tabla 1).…”

Section: ¿Cuál Es La Relación De La Covid-19 Con La Enfermedad Cardiounclassified

COVID-19, hipertensión y enfermedad cardiovascular

Salazar

Barochiner

Espeche

et al. 2020

Hipertensión y Riesgo Vascular

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COVID-19; SARS-CoV-2; Hipertensión arterial; Enfermedad cardiovascular; Pronóstico Resumen La asociación entre patología cardiovascular y mala evolución de la infección por SARS-CoV-2 resulta llamativa. Estudios publicados en diferentes países muestran que la hipertensión, la diabetes, la enfermedad cerebrovascular y la cardiopatía isquémica son marcadamente más frecuentes en los pacientes que requieren cuidados críticos o fallecen por COVID-19. Un posible nexo causal sería el daño y la disfunción miocárdica producidos por el SARS-CoV-2, evidenciado en los frecuentes hallazgos de elevación de la troponina y anormalidades electrocardiográficas. Por otra parte, existen hipótesis a favor y en contra de un posible efecto deletéreo de los inhibidores de la enzima convertidora y los bloqueantes del receptor de angiotensina 2 en esta patología, no habiendo actualmente evidencia sólida que respalde contundentemente una u otra, resultando impostergable la necesidad de estudios que diluciden este interrogante. Los pacientes con enfermedad cardiovascular deberían evitar especialmente la exposición al SARS-CoV-2, no automedicarse y consultar rápidamente ante la aparición de síntomas.

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“…The lack of any bradyarrhythmia and of recurrences is of interest as there has been concern for potential COVID‐19‐related AV block. In fact, the evidence of symptomatic bradyarrhythmias in COVID‐19 is limited to only a single case report of transient complete hear block that occurred a day after intubation and was not associated with recurrence 19 . While the authors of this manuscript have witnessed cases of complete heart block during the pandemic, coincidentally none of these presented during the 2‐week recruitment period for this study.…”

Section: Discussionmentioning

confidence: 89%

Syncope and presyncope in patients with COVID‐19

Oates

Turagam

Musikantow

et al. 2020

Pacing Clinical Electrophis

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Introduction: Recent studies have described several cardiovascular manifestations of COVID-19 including myocardial ischemia, myocarditis, thromboembolism, and malignant arrhythmias. However, to our knowledge, syncope in COVID-19 patients has not been systematically evaluated. We sought to characterize syncope and/or presyncope in COVID-19. Methods: This is a retrospective analysis of consecutive patients hospitalized with laboratory-confirmed COVID-19 with either syncope or presyncope. This "study" group (n = 37) was compared with an age and gender-matched cohort of patients without syncope ("control") (n = 40). Syncope was attributed to various categories. We compared telemetry data, treatments received, and clinical outcomes between the two groups. Results: Among 1000 COVID-19 patients admitted to the Mount Sinai Hospital, the incidence of syncope/presyncope was 3.7%. The median age of the entire cohort was 69 years (range 26-89+ years) and 55% were men. Major comorbidities included hypertension, diabetes, and coronary artery disease. Syncopal episodes were categorized as (a) unspecified in 59.4% patients, (b) neurocardiogenic in 15.6% patients, (c) hypotensive in 12.5% patients, and (d) cardiopulmonary in 3.1% patients with fall versus syncope and seizure versus syncope in 2 of 32 (6.3%) and 1 of 33 (3.1%) patients, respectively. Compared with the "control" group, there were no significant differences in both admission and peak blood levels of d-dimer, troponin-I, and CRP in the "study" group. Additionally, there were no differences in arrhythmias or death between both groups. Conclusions: Syncope/presyncope in patients hospitalized with COVID-19 is uncommon and is infrequently associated with a cardiac etiology or associated with adverse outcomes compared to those who do not present with these symptoms.

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Transient complete heart block in a patient with critical COVID-19

Cited by 78 publications

References 0 publications

Electrocardiographic Holter monitoring findings in critical coronavirus disease-19 patients

Electrocardiographic Holter monitoring findings in critical coronavirus disease-19 patients

COVID-19, hipertensión y enfermedad cardiovascular

Syncope and presyncope in patients with COVID‐19

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