“…1,[5][6][7][8] Because of its small caliber, ability in air insufflation, and the inherence of instrument channel for suction and biopsy, unsedated transnasal esophagoscopy or EGD may overcome the aforementioned difficulties in diagnosis of hypopharyngeal cancer and may be a promising standard diagnostic tool for hypopharyngeal cancer. Reviewing previous studies on the application of unsedated transnasal esophagoscopy or EGD in otolaryngology; however, most investigations have focused on benign diseases, such as globus pharyngius, reflux esophagitis, esophageal foreign body, or placement of the tracheoesophageal puncture.…”