Transomental Titanium Plates for Sternal Osteomyelitis in Cardiac Surgery

Sansone, Fabrizio; Mossetti, C; Bruna, Maria Cristina; Oliaro, A; Zingarelli, Edoardo; Flocco, Roberto; Ponte, Stefano del; Casabona, Riccardo

doi:10.1111/j.1540-8191.2011.01336.x

Cited by 8 publications

(8 citation statements)

References 10 publications

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“…We had no cases of wound infections or mediastinitis in the RM group, whereas their incidence in the MS group was about 1.5-2% [2]. No cases of empyema are reported in our series.…”

Section: In Group B (P = 004): Seven (14%) Patients In Group a Wementioning

confidence: 65%

Right minithoracotomy versus full sternotomy for the aortic valve replacement: Preliminary results

Sansone¹,

Punta²,

Parisi³

et al. 2012

Heart, Lung and Circulation

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“…We had no cases of wound infections or mediastinitis in the RM group, whereas their incidence in the MS group was about 1.5-2% [2]. No cases of empyema are reported in our series.…”

Section: In Group B (P = 004): Seven (14%) Patients In Group a Wementioning

confidence: 65%

Right minithoracotomy versus full sternotomy for the aortic valve replacement: Preliminary results

Sansone¹,

Punta²,

Parisi³

et al. 2012

Heart, Lung and Circulation

Self Cite

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“…The viability of the sternum differentiates these two entities. In Type 3 (viable sternum), sternal stabilization can be achieved with plates or clips [171][172][173][174][175][176]. Complete reconstruction can be achieved with or without the use of pectoral flaps or omentum (Class IIb, Level B).…”

Section: Management Principlesmentioning

confidence: 99%

European Association for Cardio-Thoracic Surgery expert consensus statement on the prevention and management of mediastinitis

Abu‐Omar

Kocher

Bosco

et al. 2017

Eur J Cardiothorac Surg

159

177

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Mediastinitis continues to be an important and life-threatening complication after median sternotomy despite advances in prevention and treatment strategies, with an incidence of 0.25-5%. It can also occur as extension of infection from adjacent structures such as the oesophagus, airways and lungs, or as descending necrotizing infection from the head and neck. In addition, there is a chronic form of 'chronic fibrosing mediastinitis' usually caused by granulomatous infections. In this expert consensus, the evidence for strategies for treatment and prevention of mediatinitis is reviewed in detail aiming at reducing the incidence and optimizing the management of this serious condition.

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“…The negative pressure accelerates the healing process by removing exudates, reducing bacterial load, increasing the growth of granulation tissue, favouring the contraction of the lesion margins and promoting angiogenesis (4)(5)(6). VAC therapy is applied in many fields: traumatic and dehiscent surgical wounds, acute and chronic wounds, partial-thickness burns (grade I and II), sternal osteomyelitis (7)(8)(9) and mediastinitis (10)(11)(12)(13)(14)(15)(16).…”

Section: Introductionmentioning

confidence: 99%

The effectiveness of negative pressure therapy on infected wounds: preliminary results

Torto

Ruggiero²,

Parisi

et al. 2017

International Wound Journal

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Vacuum-assisted closure (VAC) therapy is a sophisticated system that maintains a closed, humid, sterile and isolated environment. Wound infection is considered a relative contraindication. The objective of this study is to extend the indications for VAC therapy to include infected wounds by demonstrating its ability to increase the antibiotic concentration in the damaged and infected tissues. Patients who presented with ulcers infected with daptomycin-sensitive bacteria were eligible to be enrolled in this prospective study. They were given antibiotic therapy with daptomycin with a specific protocol. A biopsy of the lesion was carried out to detect tissue concentration of the drug at time 0. Afterwards, the patients were subjected to VAC therapy. At the end of VAC therapy, a second lesion biopsy was performed and analysed to detect tissue concentration of the drug at time 1. A control group was enrolled in which patients followed the same protocol, but they were treated with traditional dressings. Fisher's exact test was used to compare the two groups. The results highlighted a significant increase in the concentration of antibiotics in the study group tissue; the improvement was sensibly lower in the control group. Statistical differences were not found between the two groups. The preliminary analysis of the data showed an important increase of antibiotic concentration in the tissue after VAC therapy. Despite the encouraging data, it is necessary to broaden the sample of patients and perform the same study with other antibiotics.

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Transomental Titanium Plates for Sternal Osteomyelitis in Cardiac Surgery

Cited by 8 publications

References 10 publications

Right minithoracotomy versus full sternotomy for the aortic valve replacement: Preliminary results

Right minithoracotomy versus full sternotomy for the aortic valve replacement: Preliminary results

European Association for Cardio-Thoracic Surgery expert consensus statement on the prevention and management of mediastinitis

The effectiveness of negative pressure therapy on infected wounds: preliminary results

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