Abstract:Transoral laser microsurgery is a safe and effective initial treatment for early laryngeal cancer, and has high rates of laryngeal preservation and disease-free survival.
“…In selected cases, transoral surgery may be an alternative for major salvage surgery. In the literature, complication rates after primary treatment with CO 2 laser surgery for head and neck malignancies range from 7.5% to 22% . In the present study, a complication rate of 19% after transoral excision in previously irradiated patients was found with some severe complications such as cervical osteomyelitis and bleedings leading to death in two patients.…”
“…In selected cases, transoral surgery may be an alternative for major salvage surgery. In the literature, complication rates after primary treatment with CO 2 laser surgery for head and neck malignancies range from 7.5% to 22% . In the present study, a complication rate of 19% after transoral excision in previously irradiated patients was found with some severe complications such as cervical osteomyelitis and bleedings leading to death in two patients.…”
“…27 Five-year disease-specific survival with the CO 2 laser surgery ranged from 79% to 100%. [14][15][16][17][18][19][20][21][22][23][24][25][26] The rates of local recurrence and overall larynx preservation after endoscopic resection of Tis and T1 glottic tumors with a diode laser were reported as 8.9% and 97.6%, respectively. 29 Most of the patients who had recurrence had anterior commissure involvement.…”
Our study of microscopic diode laser resection of Tis, T1, and T2 glottic tumors showed similar oncologic results to previous reports about CO2 laser surgery. In anterior commissure tumors, both techniques had high complication and recurrence rates.
“…Transoral laser microsurgery (TLM) has been accepted as a major treatment modality for early glottic carcinoma (T1, T2), with well‐known advantages over radiation therapy (RT) and open partial laryngeal surgery . Moreover, patients offered all treatment options for early laryngeal cancer with unbiased information preferred TLM . Such a preference seems quite obvious considering the advantages of low morbidity, good functional results, lower costs, and shorter hospital stay without significant differences in local control or survival compared to other modalities .…”
Transoral CO₂ laser microsurgery as one-stage single-modality therapy resulted in a high rate of local control and a high survival rate in selected cases of early glottic carcinoma, regardless of the location of tumor and histopathology report on the surgical margin.
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