Transverse myelitis after diphtheria, tetanus, and polio immunisation.

Whittle, Ewing; Robertson, N. R. E.

doi:10.1136/bmj.1.6074.1450

Cited by 31 publications

(21 citation statements)

References 2 publications

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“…Clinical symptoms of TM usually develop over hours or days as muscle weakness and sensory disturbance below the level of the lesion, or sphincter dysfunction (6). TM following diphtheria and tetanus toxoids (Td) vaccines is very rare and only five cases have been reported before (7)(8)(9)(10)(11). Here, we report a new case of TM following administration of Td vaccine.…”

Section: Introductionmentioning

confidence: 89%

“…Only five cases of TM following Td and diphtheria-tetanus-pertussis (DTP) as single vaccines or in various combinations have been reported before. One of those cases is TM following Td vaccination, one of them is TM following oral poliovirus-Dt-Haemophilus influenzae type b vaccination and three of them are TM following DTP vaccinations (6)(7)(8)(9)(10).…”

Section: Discussionmentioning

confidence: 99%

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Difteri Tetanoz Toksoid aşısından (Td) sonra gelişen transvers myelit: Olgu sunumu

Savaş¹,

Akçam²,

Çiçek³

et al. 2013

Tftr

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Turk J Phys Med Re hab 2013;59:349-52 Türk Fiz T›p Re hab Derg 2013;59:349-52 ÖzetTransvers myelit (TM) tetanoz toksoidi içeren aşılardan sonra gelişen çok nadir bir komplikasyon olarak bildirilmiştir. Bu olgu sunumunda, erişkin tip Difteri Tetanoz Toksoid aşısı (Td) olduktan sonra kollarında ve bacaklarında progresif parestezi ve kas güçsüzlüğü gelişen kırk altı yaşında bir erkek hasta sunulmaktadır. Bu olgu literatürde Td aşısından sonra TM gelişen altıncı olgudur. Hekimler tetanoz aşısı reçete ederken bu nadir fakat ciddi yan etki konusunda uyanık olmalı; TM'in ayırıcı tanısı yapılırken aşıya bağlı gelişen TM akılda tutulmalıdır. Anah tar Ke li me ler: Tetanoz toksoid aşısı, transvers myelit, bağışıklama Sum maryTransverse myelitis (TM) has rarely been reported in association with tetanus toxoid-containing vaccines. Here, we report a 46-year-old man presented with progressive paresthesias and weakness in his arms and legs following an intramuscular injection of adult-type diphtheria and tetanus toxoids (Td). This is the sixth reported case of TM following Td vaccination. Physicians must be aware of this rare but serious side effect when prescribing Td vaccine and postvaccinial TM must be kept in mind when making a differential diagnosis of TM.

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Section: Introductionmentioning

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Difteri Tetanoz Toksoid aşısından (Td) sonra gelişen transvers myelit: Olgu sunumu

Savaş¹,

Akçam²,

Çiçek³

et al. 2013

Tftr

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“…There are some hypotheses regarding the possibility of TM following vaccination as this is not a usual adverse event [8][9][10] and the causal relationship of vaccination with TM has not yet been well established [11]. Only few (around 5) cases of TM following Tetanus toxoid (Td) and diphtheria-tetanus-pertussis (DTP) as a single vaccine or in various combinations have been reported so far [12,13]. Out of those cases; only one is TM following Td vaccination [10,[12][13][14][15].…”

Section: Case Reportmentioning

confidence: 99%

“…Only few (around 5) cases of TM following Tetanus toxoid (Td) and diphtheria-tetanus-pertussis (DTP) as a single vaccine or in various combinations have been reported so far [12,13]. Out of those cases; only one is TM following Td vaccination [10,[12][13][14][15]. The hypotheses for vaccine induced neuroinflammatory disorder emphasize on the concept of autoimmunity where there is cross reaction of antibodies and T cells to CNS and PNS neural epitopes [16].…”

Section: Case Reportmentioning

confidence: 99%

Vaccine Induced Acute Transverse Myelitis: Case Report

Chandra¹

2017

JNSK

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Acute transverse myelitis is a focal inflammatory disorder of the spinal cord [1]. One of the main etiologic factors include, multiple sclerosis, post-infectious and post-traumatic events although autoimmune phenomenon is the most common cause [2]. Transverse Myelitis (TM) due to etiology other than Multiple Sclerosis has shown spinal cord involvement of two or more segments [3]. Annually millions of active immunization with vaccines is carried out globally with little transverse myelitis caused because of the adverse reactions due to these vaccinations [4,5]. In order to improve accuracy of reporting, research and diagnosis, the Transverse Myelitis Consortium Working Group (TMCWG) has produced criteria for the diagnosis of ATM [6]. Here we report a case of TM in adult, diagnosed as TM consistent with the TMCWG criteria and probably this is the first ever been reported case from Nepal.

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“…15 Only few (around 5) cases of TM following Tetanus toxoid (Td) and diphtheriatetanus-pertussis (DTP) as a single vaccine or in various combinations have been reported so far. 17,12 Out of those cases, only one is TM following Td vaccination. 1,6,12,13,17 The hypotheses for vaccine induced neuroinfl ammatory disorder emphasize on the concept of autoimmunity where there is cross reaction of antibodies and T cells to CNS and PNS neural epitopes.…”

mentioning

confidence: 99%

Vaccine Induced Acute Transverse Myelitis: A Case Report

et al. 2016

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Acute transverse myelitis is a focal infl ammatory disorder of the spinal cord. One of the main etiologic factors include, multiple sclerosis, post-infectious and post-traumatic events although autoimmune phenomenon is the most common cause. Transverse Myelitis (TM) due to etiology other than Multiple Sclerosis has shown spinal cord involvement of two or more segments. Annually millions of active immunization with vaccines is carried out globally with few transverse myelitis caused because of the adverse reactions due to these vaccinations. In order to improve accuracy of reporting, research and diagnosis, the Transverse Myelitis Consortium Working Group (TMCWG) have produced criteria for the diagnosis of ATM. Here we report a case of TM in adult, diagnosed as TM consistent with the TMCWG criteria and probably this is the first ever been reported case from Nepal. Nepal Journal of Neuroscience. Vol. 13, No. 2, 2016, Page: 89-91

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Transverse myelitis after diphtheria, tetanus, and polio immunisation.

Cited by 31 publications

References 2 publications

Difteri Tetanoz Toksoid aşısından (Td) sonra gelişen transvers myelit: Olgu sunumu

Difteri Tetanoz Toksoid aşısından (Td) sonra gelişen transvers myelit: Olgu sunumu

Vaccine Induced Acute Transverse Myelitis: Case Report

Vaccine Induced Acute Transverse Myelitis: A Case Report

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