Traversing the epigenetic landscape: DNA methylation from retina to brain in development and disease
Chunxiu Xu,
Xuefei Fu,
Huan Qin
et al.
Abstract:DNA methylation plays a crucial role in development, aging, degeneration of various tissues and dedifferentiated cells. This review explores the multifaceted impact of DNA methylation on the retina and brain during development and pathological processes. First, we investigate the role of DNA methylation in retinal development, and then focus on retinal diseases, detailing the changes in DNA methylation patterns in diseases such as diabetic retinopathy (DR), age-related macular degeneration (AMD), and glaucoma.… Show more
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