Treatment Adherence in Patients with Hypertension: A Cross Sectional Study from Southeast of Iran

Sadeghi, Negar; Ahmadipour, Habibeh

doi:10.5812/semj.74125

Cited by 3 publications

(8 citation statements)

References 24 publications

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“…For instance, a few studies conducted in Palestine on patients with DM using the MMAS questionnaire have shown an adherence rate for DM medications between 56% and 73% [31]. A review of patients with DM in the Middle East and North Africa conducted in 2017 concluded that the average medication low adherence in this region was of 38%, compared to the 30% reported in our study [24,32,33]. The countries of the Gulf, high-income countries, appeared to be more prone to low adherence with a reported average of 40% [18,34].…”

Section: Discussioncontrasting

confidence: 57%

Self-reported medication adherence among patients with diabetes or hypertension, Médecins Sans Frontières Shatila refugee camp, Beirut, Lebanon: A mixed-methods study

Mohamad

Moussally²,

Lakis³

et al. 2021

PLoS ONE

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Introduction Low adherence to medications, specifically in patients with Diabetes (DM) and Hypertension (HTN), and more so in refugee settings, remains a major challenge to achieving optimum clinical control in these patients. We aimed at determining the self-reported medication adherence prevalence and its predictors and exploring reasons for low adherence among these patients. Methods A mixed-methods study was conducted at Médecins Sans Frontières non-communicable diseases primary care center in the Shatila refugee camp in Beirut, Lebanon in October 2018. Data were collected using the validated Arabic version of the 8-items Morisky Medication Adherence Scale (MMAS-8) concurrently followed by in-depth interviews to explore barriers to adherence in patients with DM and/or HTN. Predictors of adherence were separately assessed using logistic regression with SPSS© version 20. Manual thematic content analysis was used to analyze the qualitative data. Results Of the 361 patients included completing the MMAS, 70% (n = 251) were moderately to highly adherent (MMAS-8 score = 6 to 8), while 30% (n = 110) were low-adherent (MMAS-8 score<6). Patients with DM-1 were the most likely to be moderately to highly adherent (85%; n = 29). Logistic regression analysis showed that patients with a lower HbA1C were 75% more likely to be moderately to highly adherent [(OR = 0.75 (95%CI 0.63–0.89), p-value 0.001]. Factors influencing self-reported moderate and high adherence were related to the burden of the disease and its treatment, specifically insulin, the self-perception of the disease outcomes and the level of patient’s knowledge about the disease and other factors like supportive family and healthcare team. Conclusion Adherence to DM and HTN was good, likely due to a patient-centered approach along with educational interventions. Future studies identifying additional factors and means addressing the barriers to adherence specific to the refugee population are needed to allow reaching optimal levels of adherence and design well-informed intervention programs.

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Section: Discussioncontrasting

confidence: 57%

Self-reported medication adherence among patients with diabetes or hypertension, Médecins Sans Frontières Shatila refugee camp, Beirut, Lebanon: A mixed-methods study

Mohamad

Moussally²,

Lakis³

et al. 2021

PLoS ONE

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“…Most of the studies were published after 2015, and only 5 studies were published between 2004 and 2014. Six randomized controlled trial studies [17,21–25], one quasi-experimental study [26], and 24 cross-sectional studies [16,18–20,27–44] were identified for conducting the present study. The total number of participants in the study was 8409.…”

Section: Resultsmentioning

confidence: 99%

“…In addition, two studies used census [20,40]. Finally, 11 studies used cluster sampling [18,28,30,31,33,34,37,38,42,46].…”

Section: Resultsmentioning

confidence: 99%

“…More specifically, 17 studies used Morisky’s questionnaire which involved 8 questions [17,19,21–23,28,29,31,32,34–36,38,40,41,43,46]. Moreover, two studies used another questionnaire in addition to the MMAS-8 questionnaire [27,37]. Furthermore, four studies used the Hill-Bone questionnaire [20,25,44,45].…”

Section: Resultsmentioning

confidence: 99%

“…The factors which significantly correlated with non-adherence to drug treatment in the relevant studies were younger age [16,32,37,38,40,41,45], male gender [32,41,45], lower income [32], low level of education [37,40,41,45], living in the outskirts of the city and village [45], unemployment, and low-income job [40,45].…”

Section: Social and Economic Factorsmentioning

confidence: 99%

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Factors related to medication adherence in patients with hypertension in Iran: a systematic review study

Maleki,

Norian,

Moeini

et al. 2023

Blood Pressure Monitoring

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Objectives This study aimed to review the available studies of the factors in Iranian hypertensive patients’ adherence to drug treatment. Methods Four Persian databases and seven English databases were searched. The articles, which were published from 2000 to 2022 in Persian and English and examined the adherence to drug treatment in the Iranian population of adults with high blood pressure, were reviewed. Based on the primary examination, 31 of the initial 1062 articles met the inclusion criteria and were included in the analysis. The evidence, which was provided by the examined articles, was summarized and discussed using the 5-dimensional framework of adherence to long-term treatments, which was developed by WHO. Results The factors that significantly correlated with adherence to drug treatment in the examined studies were: (1) factors that were related to the health team or the health system: patients’ satisfaction with their doctor-patient relationship; (2) factors that were related to the conditions: the number of concomitant diseases, high quality of life and the implementation of effective interventions; (3) factors which were related to the treatment: long duration of illness, short intervals between the visits, duration of treatment, lower numbers of drugs, and the patient’s blood pressure control; and (4) factors that were related to the patient: self-efficacy, health literacy, social support, locus of control, illness perception, beliefs, attitude, knowledge, and cues to action. Conclusion: It is possible to draw definite conclusions about the factors which affect adherence to drug treatment in patients with high blood pressure because most of the relevant studies have been cross-sectional. Therefore, in the future, valuable results can be obtained by conducting more studies that preferably use objective instruments for assessing adherence to drug treatment

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The cost-effectiveness of peer education on medication adherence in the elderly with hypertension: a randomized controlled trial

Ranjbar,

Sadeghi-Vazin,

Bakhshi

2024

BMC Public Health

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Background Peer education is an effective approach for promoting medication adherence in hypertensive patients, but there is limited evidence on its cost-effectiveness analysis. This study aimed to evaluate the cost -effectiveness of peer education for improving medication adherence in the elderly with hypertension. Methods This randomized clinical trial involved 74 elderly individuals with hypertension who were referred to health centers affiliated to Mashhad University of Medical Sciences in 2019. Educational content was presented over six sessions across six weeks by a peer in the intervention group, and a health center nurse in the control group. Data was collected before the intervention, immediately after intervention, and at 3 and 6 weeks post-intervention using the Morisky Medication Adherence Scale. Data analysis was performed by SPSS (Ver. 23) with both descriptive and statistical test. Cost-effectiveness analysis of the educational methods measured the impact on medication adherence scores for each group. Results The medication adherence score was 7.33 ± 0.41 and 6.37 ± 0.76 at 6 weeks post educational sessions in the intervention and control groups, respectively. There was a significant difference in mean score of medication adherence at the end of the intervention, as well as at 3 and 6 weeks post-intervention between the groups ( p < 0.001). Additionally, the results indicated that peer education approach was more cost-effective than routine education. Conclusions Peer education programs promote medication adherence in elderly with hypertension and are more cost-effective than routine education in health centers. Healthcare managers can improve medication adherence and reduce costs with employing peers to educate older individuals with hypertension. Trial registration This study was registered in the Iranian Registry of Clinical Trials (registration number: IRCT20180519039710N1). Registration date: July 29, 2018. Supplementary Information The online version contains supplementary material available at 10.1186/s12889-024-20807-z.

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Treatment Adherence in Patients with Hypertension: A Cross Sectional Study from Southeast of Iran

Cited by 3 publications

References 24 publications

Self-reported medication adherence among patients with diabetes or hypertension, Médecins Sans Frontières Shatila refugee camp, Beirut, Lebanon: A mixed-methods study

Self-reported medication adherence among patients with diabetes or hypertension, Médecins Sans Frontières Shatila refugee camp, Beirut, Lebanon: A mixed-methods study

Factors related to medication adherence in patients with hypertension in Iran: a systematic review study

The cost-effectiveness of peer education on medication adherence in the elderly with hypertension: a randomized controlled trial

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