Trehalose mimics as bioactive compounds

Trehalose-8-hydroxyquinoline conjugates as antioxidant modulators of Aβ aggregation

“…14 Because of Tre is a relevant biological molecule in several species, considerable efforts have been invested in the design of Tre analogs, mimetics and derivatives as potential fungicides and antibiotics (especially for M. Tubercolosis). 15 In some cases, 6,6 0 -difunctionalized derivatives are biologically more active than monosubstituted compounds and show interesting biological effects. 16 To quote an example, a 6,6 0 -difunctionalized derivative known as Brartemicin, recently isolated from the actinomycete of the genus Nonomuraea inhibits cancer cell invasion.…”