Trend analysis of disability adjusted life years due to cardiovascular diseases: results from the global burden of disease study 2019

Masaebi, Fatemeh; Salehi, Masoud; Kazemi, Maryam; Vahabi, Nasim; Looha, Mehdi Azizmohammad; Zayeri, Farid

doi:10.1186/s12889-021-11348-w

Cited by 35 publications

(30 citation statements)

References 20 publications

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“…Os PLP apresentaram incremento dos riscos dietéticos e fatores metabólicos atribuíveis à mortalidade por DCVs. 21,7 7,9 22,3 20,4 33,4 32,3 2,9 24,8 28,5 17,9 20,3 25,9 19,2 17,2 15,5 25,9 21,1 25,5 17,4 24,8 18,5 28 Um estudo que analisou a carga de DCV para 194 países do mundo, de 1990 a 2019, demostrou tendência de queda dos DALYs, YLL e YLD, com taxas mais altas de YLD nas mulheres em comparação com os homens, 24 com o mesmo ocorrendo em relação à carga de DCV atribuível aos FR cardiovasculares. 4 Esses dados ressaltam a heterogeneidade dos PLP em relação à mortalidade e carga de doença, cujas variações não podem ser explicadas somente pelo SDI, com potencial contribuição de múltiplos fatores, como sexo, etnia e até mesmo diferenças culturais e ambientais.…”

Section: Discussionunclassified

Carga de Doenças Cardiovasculares Atribuível aos Fatores de Risco nos Países de Língua Portuguesa: Dados do Estudo “Global Burden of Disease 2019”

Nascimento¹,

Brant²,

Naback³

et al. 2022

Arquivos Brasileiros De Cardiologia

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Resumo Fundamento: O impacto dos fatores de risco (FR) sobre a morbimortalidade por doença cardiovascular (DCV) na maioria dos países de língua portuguesa (PLP) é pouco conhecido. Objetivo: Analisar a morbimortalidade por DCV atribuível aos FR e sua variação nos PLP de 1990 a 2019, a partir de estimativas do estudo Global Burden of Disease (GBD) 2019. Métodos: Avaliamos as mudanças nos FR ocorridas no período, as taxas de mortalidade e os anos de vida perdidos por incapacidade (DALYs), padronizados por idade, entre 1990 e 2019. Realizou-se a correlação entre a variação percentual das taxas de mortalidade e o índice sociodemográfico (SDI) de cada PLP pelo método de Spearman. O valor p<0,05 foi considerado estatisticamente significativo. Resultados: A pressão arterial sistólica (PAS) elevada foi o principal fator de risco para mortalidade e DALY por DCV para todos os PLP. A mortalidade por DCV mostrou uma tendência de redução em 2019, maior em Portugal (-66,6%, IC95% -71,0 - -61,2) e no Brasil (-49,8%, IC95% -52,5 - -47,1). Observou-se tendência à correlação inversa entre SDI e a variação percentual da mortalidade, que foi significativa para os riscos dietéticos (r=-0,70, p=0,036), colesterol LDL elevado (r=-0,77, p=0,015) e PAS elevada (r=-0,74, p=0,023). Conclusões: Além da PAS, os FR dietéticos e metabólicos justificaram uma maior variação da carga de DCV, correlacionada com o SDI nos PLP, sugerindo a necessidade de adoção de políticas de saúde adaptadas à realidade de cada país, visando a redução de seu impacto sobre a população.

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Section: Discussionunclassified

Carga de Doenças Cardiovasculares Atribuível aos Fatores de Risco nos Países de Língua Portuguesa: Dados do Estudo “Global Burden of Disease 2019”

Nascimento¹,

Brant²,

Naback³

et al. 2022

Arquivos Brasileiros De Cardiologia

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“…For people with diabetes, improved DFLE may be from lifestyle interventions such as weight loss and physical activity [ 43 ]. Healthier lifestyles and improved access to treatment may also have contributed to the improvement in CHD DFLE [ 44 ]. Further gains could be made through earlier diagnosis and greater access to beneficial treatments, although delays in screening, diagnosis, and treatment resulting from the Coronavirus Disease 2019 (COVID-19) pandemic may have a detrimental impact.…”

Section: Discussionmentioning

confidence: 99%

A comparison over 2 decades of disability-free life expectancy at age 65 years for those with long-term conditions in England: Analysis of the 2 longitudinal Cognitive Function and Ageing Studies

et al. 2022

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Background Previous research has examined the improvements in healthy years if different health conditions are eliminated, but often with cross-sectional data, or for a limited number of conditions. We used longitudinal data to estimate disability-free life expectancy (DFLE) trends for older people with a broad number of health conditions, identify the conditions that would result in the greatest improvement in DFLE, and describe the contribution of the underlying transitions. Methods and findings The Cognitive Function and Ageing Studies (CFAS I and II) are both large population-based studies of those aged 65 years or over in England with identical sampling strategies (CFAS I response 81.7%, N = 7,635; CFAS II response 54.7%, N = 7,762). CFAS I baseline interviews were conducted in 1991 to 1993 and CFAS II baseline interviews in 2008 to 2011, both with 2 years of follow-up. Disability was measured using the modified Townsend activities of daily living scale. Long-term conditions (LTCs—arthritis, cognitive impairment, coronary heart disease (CHD), diabetes, hearing difficulties, peripheral vascular disease (PVD), respiratory difficulties, stroke, and vision impairment) were self-reported. Multistate models estimated life expectancy (LE) and DFLE, stratified by sex and study and adjusted for age. DFLE was estimated from the transitions between disability-free and disability states at the baseline and 2-year follow-up interviews, and LE was estimated from mortality transitions up to 4.5 years after baseline. In CFAS I, 60.8% were women and average age was 75.6 years; in CFAS II, 56.1% were women and average age was 76.4 years. Cognitive impairment was the only LTC whose prevalence decreased over time (odds ratio: 0.6, 95% confidence interval (CI): 0.5 to 0.6, p < 0.001), and where the percentage of remaining years at age 65 years spent disability-free decreased for men (difference CFAS II–CFAS I: −3.6%, 95% CI: −8.2 to 1.0, p = 0.12) and women (difference CFAS II–CFAS I: −3.9%, 95% CI: −7.6 to 0.0, p = 0.04) with the LTC. For men and women with any other LTC, DFLE improved or remained similar. For women with CHD, years with disability decreased (−0.8 years, 95% CI: −3.1 to 1.6, p = 0.50) and DFLE increased (2.7 years, 95% CI: 0.7 to 4.7, p = 0.008), stemming from a reduction in the risk of incident disability (relative risk ratio: 0.6, 95% CI: 0.4 to 0.8, p = 0.004). The main limitations of the study were the self-report of health conditions and the response rate. However, inverse probability weights for baseline nonresponse and longitudinal attrition were used to ensure population representativeness. Conclusions In this study, we observed improvements to DFLE between 1991 and 2011 despite the presence of most health conditions we considered. Attention needs to be paid to support and care for people with cognitive impairment who had different outcomes to those with physical health conditions.

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“…Постійний моніторинг захворюваності, інвалідності та смертності, спричиненої ХСК є важливою передумовою ефективного управління станом громадського здоров'я, організації якісної і доступної медичної та медико-соціальної допомоги пацієнтам із ХСК [9,10]. У зв'язку із відміною в Україні (у 2018 р.)…”

Section: вступunclassified

Current trends and regional peculiarities of disability due to cardiovascular diseases in Ukraine

Kovtun¹,

Orlova²

2022

Rep. of Vinnytsia Nation. Med. Univ.

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Annotation. Cardiovascular diseases (CVD) are the leading cause of premature death and disability in Ukraine, which determines their significant medical, social and economic significance. The aim of the study was to analyze the general trends and regional characteristics of primary disability due to CVD in Ukraine in 2010-2020. The dynamic analysis was carried out using such indicators as absolute growth (AGr) and growth rate (GR). Such parameters as minimum, maximum territorial value, median, amplitude of a series of regional distribution of indicators, upper lower quartile, coefficient of regional variation were also analyzed. The stability of territorial characteristics of primary disability due to CVD in Ukraine was determined using the Pearson correlation coefficient (r). The comparison of disability caused by CVD in Ukraine and the countries of Europe and the European Union was carried out on the basis of the indicator of DALYs calculated per 100 000 population. Materials obtained from the statistical database of the international epidemiological study “Global Burden of Disease”, updated for 2019, were used for the analysis. With the help of the medical-statistical method, the materials of the state statistical reporting (form № 14) regarding primary disability caused by CVD in Ukraine and its regions in 2019-2020 were analyzed. A trend towards a decrease in primary disability caused by CVD among the adult population (by 19.6%, from 11.2 in 2010 to 9.0 per 10,000 in 2020) and among working-age population (by 11.5%, from 10.4 to 9.2 per 10,000, respectively) was determined. At the same time, CVD continues to be the leading cause of disability in the adult and working-age population with a share in the structure of primary disability of 23.5% and 21.2%, respectively. It has been established that in 73.1% of cases, primary disability due to CVD is formed at the age less than 55 for women and 60 years for men. The loss of life years due to disability caused by CVD in Ukraine is 1.2 times higher than in European countries and 1.4 times higher than in the European Union. Cerebrovascular disease account for almost half (45.3% for adults and 44.8% for the population of working age), and coronary heart disease for a third (33.2% and 35.4%, respectively) of all cases of primary disability, caused by CVD. The study identified regions of Ukraine with high levels and increasing of primary disability due to CVD. Reduction in the disability of the population of Ukraine and its regions requires the improvement of primary and secondary prevention of CVD, increasing the efficiency of rehabilitation of patients with CVD, and optimizing cardiological and cardiac surgical care. Our further research will be aimed at substantiating the possibilities of improving the organization of cardiac surgical care for the population of Ukraine.

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Trend analysis of disability adjusted life years due to cardiovascular diseases: results from the global burden of disease study 2019

Cited by 35 publications

References 20 publications

Carga de Doenças Cardiovasculares Atribuível aos Fatores de Risco nos Países de Língua Portuguesa: Dados do Estudo “Global Burden of Disease 2019”

Carga de Doenças Cardiovasculares Atribuível aos Fatores de Risco nos Países de Língua Portuguesa: Dados do Estudo “Global Burden of Disease 2019”

A comparison over 2 decades of disability-free life expectancy at age 65 years for those with long-term conditions in England: Analysis of the 2 longitudinal Cognitive Function and Ageing Studies

Current trends and regional peculiarities of disability due to cardiovascular diseases in Ukraine

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