Trends in Asthma Mortality in the United States: 1999 to 2015

Pennington, Emily; Yaqoob, Zaid; Al‐Kindi, Sadeer G.; Zein, Joe

doi:10.1164/rccm.201810-1844le

Cited by 51 publications

(31 citation statements)

References 10 publications

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“…Asthma is a highly prevalent, chronic, non-communicable disease that affects up to 4.4% of the world’s population ( http://www.globalasthmareport.org ; https://www.who.int/news-room/q-a-detail/asthma ). Its recurrent nature leads to frequent hospitalizations and high mortality, ranging from 2 to 4/100,000 [ 13 ]. Respiratory viruses can trigger asthma exacerbations, which can increase the severity of the infectious condition [ 14 ].…”

Section: Discussionmentioning

confidence: 99%

Asthma and COVID-19: a systematic review

Mendes

Jara

Mansour

et al. 2021

Allergy Asthma Clin Immunol

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Background Severe coronavirus disease-19 (COVID-19) presents with progressive dyspnea, which results from acute lung inflammatory edema leading to hypoxia. As with other infectious diseases that affect the respiratory tract, asthma has been cited as a potential risk factor for severe COVID-19. However, conflicting results have been published over the last few months and the putative association between these two diseases is still unproven. Methods Here, we systematically reviewed all reports on COVID-19 published since its emergence in December 2019 to June 30, 2020, looking into the description of asthma as a premorbid condition, which could indicate its potential involvement in disease progression. Results We found 372 articles describing the underlying diseases of 161,271 patients diagnosed with COVID-19. Asthma was reported as a premorbid condition in only 2623 patients accounting for 1.6% of all patients. Conclusions As the global prevalence of asthma is 4.4%, we conclude that either asthma is not a premorbid condition that contributes to the development of COVID-19 or clinicians and researchers are not accurately describing the premorbidities in COVID-19 patients.

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Section: Discussionmentioning

confidence: 99%

Asthma and COVID-19: a systematic review

Mendes

Jara

Mansour

et al. 2021

Allergy Asthma Clin Immunol

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“…The lack of mortality trend in age groups 5 to 9 or 10 to 14 years is consistent with the findings of a recent multi country study that found no significant changes in mortality from 2006 to 2012 34 in the group that included a combination of asthmatic children and adults (age 5‐34 years). The recent US study 14 from 1999 to 2015 did not show changes in asthma mortality either with low mortality rates in children aged 1 to 14.…”

Section: Discussionmentioning

confidence: 83%

“…Some of these studies, including an old Mexican study, 13 reported a favorable decreasing trend of asthma mortality overtime. Contrary to this, a recent US study found no significant changes from 1999 to 2015 and low mortality rate in children aged 1 to 14 14 . However, analysis by zone of residence was not performed neither the Mexican nor US studies.…”

Section: Introductionmentioning

confidence: 76%

Asthma mortality among Mexican children: Rural and urban comparison and trends, 1999‐2016

Hernández‐Garduño

2020

Pediatric Pulmonology

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Objective Although there are more studies showing higher asthma prevalence in urban rather than rural zones, few assessed asthma mortality by zone in children. The objective of this study is to compare asthma mortality rates (AMR) by zone of residence of Mexican children. Design Using national death certificate and population projections data, AMR were compared in children aged 0 to 14 years by gender, age group, and zone of residence from 1999 to 2016. AMR trends were calculated using Joinpoint regression. Results Of the 680 823 deaths, 2464 (0.36%) were due to asthma. Asthma mortality was higher in rural (0.65%) than urban (0.26%) zones, P < .0001. Whole period AMR median was also higher in rural vs urban zones (0.6 vs 0.3, respectively), P < .05. The average annual percent change (AAPC) of AMR for the whole period was −5.1 in all children with a higher percent decrease in rural vs urban zones (girls' AAPC = −6.3 vs −4.1, respectively and boys' AAPC = −4.8 vs −4.2, respectively). AMR decreased in children aged 0 to 4 from both zones (rural's AAPC: girls = −7.9, boys = −5.2; urban's AAPC: girls = −5.1, boys = −5.4), P < .05. No trend was found in children aged 5 to 14. Conclusions Asthma mortality in Mexican children is higher in rural than urban zones. The decrease of mortality over time in early childhood is reassuring. More research is needed to determine reasons for higher mortality in rural Mexico and for the lack of a favorable decreasing trend in children aged 5 to 14 from both zones.

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“…Asthma is a highly prevalent, chronic, non-communicable disease that affects up to 4.4% of the world's population (http://www.globalasthmareport.org; https://www.who.int/news-room/q-a-detail/asthma). Its recurrent nature leads to frequent hospitalizations and high mortality, ranging from 2 to 4/100,000 (13).…”

Section: Discussionmentioning

confidence: 99%

Asthma and COVID-19 - A systematic review

Mendes

Jara

Mansour

et al. 2020

Preprint

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Background. Severe coronavirus disease-19 (COVID-19) presents with progressive dyspnea, which results from acute lung inflammatory edema leading to hypoxia. As with other infectious diseases that affect the respiratory tract, asthma has been cited as a potential risk factor for severe COVID-19. However, conflicting results have been published over the last few months and the putative association between these two diseases is still unproven. Methods. Here, we systematically reviewed all reports on COVID-19 published since its emergence in December 2019 to June 30, 2020, looking into the description of asthma as a premorbid condition, which could indicate its potential involvement in disease progression. Results. We found 372 articles describing the underlying diseases of 161,271 patients diagnosed with COVID-19. Asthma was reported as a premorbid condition in only 2,623 patients accounting for 1.6% of all patients. Conclusions. As the global prevalence of asthma is 4.4%, we conclude that either asthma is not a premorbid condition that contributes to the development of COVID-19 or clinicians and researchers are not accurately describing the premorbidities in COVID-19 patients.

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Trends in Asthma Mortality in the United States: 1999 to 2015

Abstract: In-vitro evaluation of contrast media for assessment of regional perfusion distribution by electrical impedance tomography (EIT).

Cited by 51 publications

References 10 publications

Asthma and COVID-19: a systematic review

Asthma and COVID-19: a systematic review

Asthma mortality among Mexican children: Rural and urban comparison and trends, 1999‐2016

Asthma and COVID-19 - A systematic review

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