Trends in Multiresidue Analysis

Abstract

The global concern about food safety and environment quality has produced the development of a legal framework to control residues of organic compounds (e.g. pesticides and veterinary and human drugs). In this context, the establishment of analytical methods achieving satisfactory performances in terms of sensitivity, selectivity, resolution, identification, sample throughput, and applicability has been mandatory. Multiresidue methods based on chromatographic techniques, mainly gas chromatography (GC) and liquid chromatography (LC), coupled to mass spectrometry (MS), have been applied and sample preparation has evolved through the development of miniaturized and environmentally friendly procedures according to the Green Chemistry. In addition, generic extraction procedures for multiclass analysis have been optimized, increasing sample throughput. Capillary electrophoresis (CE) has emerged as an alternative to LC and GC, owing to the development of on‐line preconcentration strategies for increasing sensitivity. This article aims to show an overview about the current trends in the analysis of pesticide and drugs in food and environmental samples, discussing the relevant advances in sample treatments and the technological evolution of the instrumental techniques. We hope to offer with this article a critical review of the analytical possibilities for routine analysis laboratories.

Modern Extraction and Cleanup Methods of Veterinary Drug Residues in Food Samples of Animal Origin

“…Veterinary drug residues in food of animal origin are of great concern to regulatory agencies and consumers, hence reliable extraction methods for rapid, selective and sensitive detection of these residues are necessary to ensure food safety [29]. There are various extraction methods that have been used in veterinary drug residues analysis in food samples, such as liquid-liquid extraction (LLE) [30][31][32] and solid phase extraction (SPE) [33,34]. These methods suffer a number of drawbacks even though they perform their tasks adequately.…”

Evaluation of a new modified QuEChERS method for the monitoring of carbamate residues in high‐fat cheeses by using UHPLC–MS/MS

“…Henceforth, it is critical to develop highly sensitive methods for the determination of these pesticides in scarcely explored samples with high fat content, such as some dairy products. LC or GC coupled with MS or MS/MS detection has been generally used for the determination of pesticides in foods . Several methods for the determination of pesticide residues in milk and dairy products can be found in literature , using GC–MS and, more frequently LC–MS and LC–MS/MS .…”