Trends in the annual risk of tuberculous infection in India

Abstract

Although a decline in ARTI was observed in two of the four zones and at national level, the current ARTI of about 1% in three zones suggests that further intensification of TB control activities is required.

Antimycobacterial Drugs Modulate Immunopathogenic Matrix Metalloproteinases in a Cellular Model of Pulmonary Tuberculosis

“…The study was conducted in collaboration with a university hospital in eastern India. According to the 2011 WHO report, India has the highest TB burden in the world, with an annual incidence of 2.2 million cases (42)(43)(44)(45). In response, India runs the world's largest health care program for the eradication of TB under its revised national TB control program (RNTCP) (46), but the problem is compounded by poverty (47), poor compliance, and more recently the surge in drug resistance (48)(49)(50).…”

Tackling the Problem of Tuberculosis by Nanotechnology

“…In India, the ARI showed regional variations; it was higher in the northern (1.9%) and western (1.8%) zones compared with the eastern (1.3%) and southern (1%) zones (Chadha et al, 2005;Sharma and Mohan, 2013). However, in house-based tuberculin surveys conducted among children aged 1 to 9 years in statistically selected clusters during 2000 to 2003 and 2009 to 2010, it was observed that ARI rates decreased by, respectively, 6% and 11.7% per year in the north and west zones; however, no change was evident in the south and east zones.…”

“…However, in house-based tuberculin surveys conducted among children aged 1 to 9 years in statistically selected clusters during 2000 to 2003 and 2009 to 2010, it was observed that ARI rates decreased by, respectively, 6% and 11.7% per year in the north and west zones; however, no change was evident in the south and east zones. In India, ARI decreased by 4.5% per year between 1998 and 2007 (Chadha et al, 2013).…”

Interferon Gamma Release Assay and Tuberculin Skin Test in the Diagnosis of Latent Tuberculosis among Health Care Workers – A Comparative Study

“…The ARTI among medical and nursing trainees has been estimated to be approximately 5% , which is substantially higher than the ARTI in the general population which is estimated at 1.5% (Chadha et al, 2005).…”