Triazole-based novel bis Schiff base colorimetric and fluorescent turn-on dual chemosensor for Cu²⁺ and Pb²⁺: application to living cell imaging and molecular logic gates

Abstract

A novel triazole-based bis Schiff base colorimetric and fluorescent chemosensor (L) has been designed, synthesized and characterized. The chemo-sensor L shows its application potential in the detection of Cu2+ and Pb2+ in living cells and building molecular logic gate.

A novel dihydro phenylquinazolinone-based two-in-one colourimetric chemosensor for nickel(ii), copper(ii) and its copper complex for the fluorescent colourimetric nanomolar detection of the cyanide anion

“…Dihydro phenylquinazolinone derivatives are an important class of compounds as inhibitors of cell multiplication and well known as antiarthritic and antispermatogenic drugs. 57,58 Herein, in continuation of our ongoing research on the recognition of different analytes using simple chemosensors, [59][60][61] we report a simple, easy to prepare, and cost effective colourimetric chemo-sensor, 3-[(E)-(2-hydroxybenzylidene)amino]-1,2-dihydro-2-phenylquinazolin-4(3H)-one (L), for the sensitive and selective detection of Ni 2+ and Cu 2+ ions and its copper complex for both the colourimetric and uorometric detection of CN À ions. The chemosensor L detected the presence of the cations Ni 2+ and Cu 2+ by both uorescence quenching and an instant change in colour from colourless to yellow, and its Cu 2+ complex detected CN À ions by uorescence enhancement and colour change from yellow to colourless.…”

Fluorescent Schiff base sensors as a versatile tool for metal ion detection: strategies, mechanistic insights, and applications

“…Charge transfer 2). 75 In methanol-tris buffer (1 : 1) medium, the free sensor displayed weak emission at 440 nm (l ex = 340 nm), attributed to the PET process from the triazole and imine moiety to the fluorophore. In the presence of Cu 2+ /Pb 2+ , the fluorescence spectrum of sensor 6 displayed an increase in emission intensity attributed to blockage of the PET process and strengthening of the ICT process.…”

A fluorescent colorimetric vanillin di-Schiff base chemosensor for detection of Cu(ii) and isolation of trinuclear Cu(ii)–dihydrazide

“…In our ongoing research we have already reported several multiple amides based [45], triazole based [46], dihydrazone based [47], dihydrophenylquinazolinone-based [48], thiosemicarbazone based [49], benzohydrazide based [50,51] chemosensors for Cu(II). Taking another step in the process of searching for suitable chemosensor we have focused on dihydrazone based 3 chemosensors.…”