Trichoscopy of whorled alopecia revealing “pigment incontinence” of incontinentia pigmenti

T, Muhammed Razmi; Jogunoori, Swathi; Radotra, Bishan Das; De, Dipankar

doi:10.1111/ijd.14481

Cited by 3 publications

(5 citation statements)

References 6 publications

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“…In In dermoscopy of IP stage III, the main dermoscopic differential diagnosis is presented in Table 2. Linear brown to gray-brown dots are in accordance with previous 2 reports of IP dermoscopy of pigment stage [16,17]. Perifollicular depigmentation and disruptions in the normal reticular pigmentation of the surrounding skin have been observed.…”

Section: Discussionsupporting

confidence: 91%

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Dermatoscopy in the Diagnostics of Incontinentia Pigmenti Skin Lesions

Minić

Dobrosavljevic

Lalošević

et al. 2022

Dermatol Pract Concept

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Introduction: Incontinentia pigmenti (IP) is a rare X-linked geno-dermatosis characterized by numerous findings. Skin biopsy and histopathological analysis are considered as minor criteria for the diagnosis of IP. We assume that dermoscopy can assist the earlier diagnosis of IP. Objectives: To gain experience in earlier diagnosis of IP by observing dermoscopic findings of cutaneous changes. Methods: We revised confirmed cases of IP and examined them using dermoscopy, comparing histopathological and dermoscopic results. Results: Stage I presented solitary and grouped vesicles in linear arrangement on erythematous skin. Early stage II presented star-shaped verrucous lesions on erythematous or pigmented skin. In well-developed lesions, dotted vessels surround keratotic part, some with thrombosed capillaries, resembling a viral wart. Stage III presented linear brown dots on the pigmented areas. Dermoscopic image was uniform in all the examined pigmented Blaschko linear changes. Stage IV presented numerous dotted vessels on the hypopigmented skin. Terminal hair was scarce or absent in all four stages. The surrounding normal skin had perifollicular depigmentations in stages III and IV. Conclusions: Dermoscopy of all four stages is very specific compared to the dermoscopy of inflammatory dermatoses and pigmentations. Stage III has very close clinical, histological and dermoscopic mimickers and needs to be carefully examined with obligatory genetic testing. Dermoscopy of the stage IV closely corresponds to histopathological findings and may be crucial as a quick tool in revealing potential IP gene carriers. Dermoscopy should be used in addition to clinical examination since the two methods are complementary.

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Section: Discussionsupporting

confidence: 91%

“…There have been only 2 cases of IP dermoscopy published so far: one with positive genetic findings, lacking a histology analysis, the other on dermoscopy on IP whorled alopecia and with no report on IKBKG gene analysis [16,17].…”

Section: Discussionmentioning

confidence: 99%

Dermatoscopy in the Diagnostics of Incontinentia Pigmenti Skin Lesions

Minić

Dobrosavljevic

Lalošević

et al. 2022

Dermatol Pract Concept

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

“…There are few reports on dermoscopic and trichoscopic findings in IP cases ( 10 , 11 ). On trichoscopic examination of whorled alopecia in IP patient, Razmi et al reported blue-grey pigment dots, empty hair follicles, and black dots ( 11 ). Similarly, we reported grey-brown globules and empty hair follicles, as well as yellowish structureless areas and thin hair.…”

Section: Discussionmentioning

confidence: 99%

“…On the other hand, dermoscopy can be a useful diagnostic tool in cutaneous lesions of IP. On dermoscopic findings in the pigment stage of IP, Bishnoi et al reported linear brown to grey-brown dots ( 10 , 11 ) and Minic et al showed linear grey to grey-brown dots on the light-brown pigmented background that intermingled with normal skin and perifollicular depigmentation ( 14 ). Similarly, we showed linear distributed grey-brown dots on the brown pigmented background.…”

Section: Discussionmentioning

confidence: 99%

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