Natural ventilation is a way to reduce the energy consumption of building operations and improve the indoor living environment comfort. The venturi cap is designed with a roof, grille and wind deflector to intensify the natural ventilation of buildings. The structural parameters of the venturi cap were designed using an orthogonal design. Fluid analysis software was used for numerical simulation, and variance analysis was used to study the importance of seven influence factors: the width of the roof opening, the roof slope, the height of the wind deflector, the horizontal width of the wind deflector, the angle of the wind deflector, the angle of the grille, and the spacing of the grille slices. The results show that the most significant influencing factor is the width of the roof opening, while significant influence factors include the angle of the grille and the horizontal width of the wind deflector. Additionally, the optimum parameter combination for ventilation performance at the research level was put forward, with the proposed combination achieving a volume flow rate of 5.507 m3/s. The average temperature of the horizontal plane at a height of 1.2 m above the ground was 3.002 K lower than that without a venturi cap, which provides a reference for the optimization of indoor ventilation design in buildings in the Xichang area.