2023
DOI: 10.7717/peerj.16316
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TTC13 expression and STAT3 activation may form a positive feedback loop to promote ccRCC progression

Lingling Xie,
Yu Fang,
Jianping Chen
et al.

Abstract: Background Renal cell carcinoma (RCC) originates from renal tubular epithelial cells and is mainly classified into three histological types, including clear cell renal cell carcinoma (ccRCC) which accounts for about 75% of all kidney cancers and is characterized by its strong invasiveness and poor prognosis. Hence, it is imperative to understand the mechanisms underlying the occurrence and progression of ccRCC to identify effective biomarkers for the early diagnosis and the prognosis prediction.… Show more

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