Tuba plant is a species of Derris that can be found in Southeast Asia such as Indonesia, Malaysia, Brunai, Thailand and the Philippines. This plant contains the toxic substance rotenone and is used by the community as a poison to catch fish. The toxicity of rotenone to fish varies between species. Therefore, there is a significant risk of non-target fish species being poisoned when rotenone is used. In addition to poisoning fish, this substance can be used to kill corn cob borers, kill cat lice, eradicate rice snails, and control caterpillar populations. The results of the review of rotenone contained in tuba plants from several studies show that the use of rotenone is effective for eradicating pests, including in Fisheries Management can eradicate unwanted pests and predatory fish, exterminating corn cob borers can control cob borers (Helicoverpa armigeran Hubner) with an initial death time of 26, 50 hours, LT50 67.50 hours and total larval mortality 87.5%, Cat lice repellent can kill cat lice (Siphonaptera), exterminate paddy snails by giving 75% and 100% tuba root extract concentration, and control the population of caterpillars by giving 50% rotenone extract. It can therefore be concluded that that tuba root extract (Derris elliptica) can be used as a vegetable pesticide because it is proven to be effective in eradicating fisheries management pests, borers on corn cobs, lice pests in cats, rice snails in rice plants, and caterpillar pests in fruit plants.