Tuberculoma of the anterior optic pathways

Abstract

A tuberculoma, encasing the anterior optic pathways in a neoplastiform growth, was found in a 25-year-old man complaining of severe visual loss, diabetes insipidus, and sexual impotence following tuberculous meningitis. Following biopsy and anti-tuberculosis treatment, a satisfactory restoration of sight in one eye allowed the patient to resume an almost normal life.

Miliary Tuberculosis Associated with Multiple Intracranial Tuberculomas

“…However, the tuberculomas, those are sufficient in number and size to make focal neurological signs and to increase the intracranial pressure, demonstrate clinical signs (Iraci et al 1980).…”

Suprasellar Tuberculoma Causing Endocrinologic Disorders and Imitating Craniopharyngioma

“…Although there have been a few reports of children with intra-or suprasellar tuberculoma in the recent litera ture [17,18], we found only the 3 adult cases who had both sellar tuberculoma and pituitary failure [22][23][24], Our case is the first child with both states.…”

“…One was a 25-year-old man with a tuberculoma encasing the anterior optic pathways, and he had severe visual loss, diabetes insipidus, and sexual impotence following tuberculous meningitis [22], The second was a 45-year-old woman with an isolated tuberculous granuloma of the hypophysis with no other systemic localizations [24], The third was a 37-year-old woman with intra-and suprasellar tuberculo ma and hypopituitarism [23].…”

Optic Neuropathy From Bacteria

“…Optic neuropathy may occur because of inflammation of the nerve, meningeal infiltration (''arachnoiditis''), or by tuberculoma compression of the nerve or its' blood supply. [20][21][22] Most, but not all, patients have concomitant tuberculous meningitis. 23 Extrapulmonary tuberculosis is treated with isoniazid (INH), rifampin, and pyrazinamide for 2 months, followed by INH and rifampin for 7 more months.…”