Tuberculose cérébrale : à propos de 21 cas

Elmamoune, A.; Souylem, M.B.; Kleib, A.S.; Memou, S.; Soumaré, Outouma; Salihy, S.M.

doi:10.1016/j.neuchi.2019.03.008

Cited by 2 publications

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“…CNS tuberculosis is common in developing countries. It has been on the rise in industrialized countries since the advent of HIV 1 infection [4]. CNS involvement can take three forms of unequal frequency: tubercular meningitis, tuberculomas, and, exceptionally, tubercular abscesses [9].…”

Section: Discussionmentioning

confidence: 99%

“…It is on the rise in developed countries, especially since the AIDS pandemic [3]. Cerebral intraparenchymal tuberculosis accounts for 10-30% of intracranial expansive processes in developing countries [4][5][6] where it remains endemic and associated with high morbidity and mortality despite advances in imaging and treatment. Despite their low frequency (1% of extrapulmonary tuberculosis cases) [7], they occupy a special place because of their poor prognosis, mainly due to the delay in treatment.…”

Section: Introductionmentioning

confidence: 99%

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Cerebral abscesses of tuberculosis origin: study of 8 cases at the University Hospital of Conakry

et al. 2020

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Introduction Tuberculosis of the central nervous system (CNS) remains endemic in developing countries with high morbidity and mortality despite advances in imaging and treatment. The objective of our work was to describe the diagnostic and therapeutic difficulties of this pathology in the context of a country with limited health resources. Materials and methods We retrospectively studied 8 cerebral tuberculosis abscess files, collected in the archives of the neurosurgery department of the Conakry University Hospital over a 5-year period (January 2013–December 2017). The diagnosis was made by scanning and by isolation of acid-fast bacilli (AFB) by direct examination of pus. Results Mean age was 33 years (9–56 years), sex, 5H 5 men/3F 3 women. History of pulmonary TB, 3 cases; TB contagious, 5 cases; TST ITR positive, 5 cases; associated visceral TB, 5 cases; HIV positive serology, 2 cases. The clinic was dominated by altered consciousness, 7 cases; focal signs, 7 cases; and fever, 5 cases. The site was hemispherical in 7 cases and one case in the posterior brain fossa. Treatment was medico-surgical in all patients. The evolution was favorable in 3 cases, the neurological sequelae in 3 cases, 2 cases of death, and 2 cases of recurrence. Conclusion Cerebral tuberculous abscesses constitute a medico-surgical emergency. Despite their rarity, morbidity and mortality remains high in the context of developing countries due to diagnostic and therapeutic delays.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Cerebral abscesses of tuberculosis origin: study of 8 cases at the University Hospital of Conakry

et al. 2020

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The Long‐Term Journey of a Tuberculosis Patient With Triple Organ Involvement and Rheumatological Disease: A Case Study and Literature Review

Saffar,

Sobhanian,

Alian

et al. 2024

Clinical Case Reports

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Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis bacteria, which is more prevalent among immunocompromised individuals. According to the distribution of affected organs, this infection can be categorized as either pulmonary or extrapulmonary TB. Immunodeficiency states resulting from rheumatological disorders and the use of immunosuppressive medications, such as in Behçet's disease (BD), are potential predisposing factors for TB, particularly in cases involving multiple organs. These situations can introduce challenges in both the diagnosis and treatment of patients. We describe a 43‐year‐old man with a history of BD who presented with symptoms of weight loss, abdominal pain, and shortness of breath. His chest X‐ray revealed cavities and calcifications, while an abdominal X‐ray demonstrated signs of intestinal obstruction and adhesions. Subsequent TB diagnosis led to a 6‐month course of a TB treatment regimen. Despite treatment initiation, the patient developed a brain abscess 1 year later, necessitating surgical intervention. Following the procedure, he received another 1‐year course of a TB treatment regimen and experienced full recovery without any complications during a 2‐year follow‐up period. Notably, the patient recently received a Sinopharm COVID‐19 vaccine and subsequently developed seizures that are currently being managed with anticonvulsant therapy. This case report emphasizes the significance of including pulmonary TB in complex medical cases, especially in individuals with autoimmune diseases. Early diagnosis and treatment are crucial for improving outcomes and reducing the risk of complications. Furthermore, it highlights the possible correlation between TB and BD, along with the potential adverse reactions to COVID‐19 vaccines in this population, which necessitate special consideration by healthcare professionals.

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Tuberculose cérébrale : à propos de 21 cas

Cited by 2 publications

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Cerebral abscesses of tuberculosis origin: study of 8 cases at the University Hospital of Conakry

Cerebral abscesses of tuberculosis origin: study of 8 cases at the University Hospital of Conakry

The Long‐Term Journey of a Tuberculosis Patient With Triple Organ Involvement and Rheumatological Disease: A Case Study and Literature Review

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