Tuberculosis burden in immigrants and natives, adults and children, in Tuscany between 2000–2018

Panin, Fiorenza; Orlandini, Elisa; Galli, Luisa; Martino, Maurizio de; Chiappini, Elena

doi:10.1016/j.tmaid.2021.102185

Cited by 2 publications

(3 citation statements)

References 53 publications

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“…14 In another retrospective study conducted in 31 hospitals in Tuscany for the incidence of TB, it was determined that South Asian-born patients were at increased risk of EPTB. 15 Another study of 37 patients diagnosed with the genitourinary TB in an East London Hospital reported that 65% of patients were born in the South Asian region. 16 There is also some evidence that ethnicityrelated characteristics, such as polymorphisms and haplotypes, significantly influence how the host immune system responds to MTBC infectionsg.…”

Section: Susceptibility Of Extrapulmonary Tb In South Asiansmentioning

confidence: 99%

“…A data set of 902 extrapulmonary Mycobacterium tuberculosis complex (MTBC) isolates from Saudi Arabia revealed that South Asian ethnicities were more strongly associated with EPTB 14 . In another retrospective study conducted in 31 hospitals in Tuscany for the incidence of TB, it was determined that South Asian‐born patients were at increased risk of EPTB 15 . Another study of 37 patients diagnosed with the genitourinary TB in an East London Hospital reported that 65% of patients were born in the South Asian region 16 .…”

Section: Susceptibility Of Extrapulmonary Tb In South Asiansmentioning

confidence: 99%

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Better understanding extrapulmonary tuberculosis: A scoping review of public health impact in Pakistan, Afghanistan, India, and Bangladesh

Jawed

Tharwani

Siddiqui

et al. 2023

Health Science Reports

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Background and Aims: South Asian countries, including Pakistan, Afghanistan, India, and Bangladesh, have a high prevalence of pulmonary and extra-pulmonary tuberculosis (EPTB). This prevalence is influenced by various risk factors such as ethnicity, nutrition, socioeconomic disparities, high out-of-pocket healthcare expenses, and specific Mycobacterium Tuberculosis (TB) lineages. The COVID-19 pandemic has likely hindered access to healthcare and led to under-reporting of EPTB cases nationally and internationally. This rapid review aimed to summarize the literature on the prevalence and disease outcomes of EPTB in the mentioned countries, compare the situations across countries, and provide recommendations for future action. Methods: The review utilized PubMed and Google Scholar databases to search for literature on EPTB in South Asian countries. The search string included keywords related to different forms of EPTB and the countries of interest while excluding pulmonary tuberculosis. Results:The results showed that both TB, including drug-resistant TB, and EPTB are prevalent and burdensome in South Asia. In Pakistan, pleural TB was the most commonly reported form of EPTB, followed by lymph node TB, abdominal TB, osteoarticular TB, Central Nervous System TB, and miliary TB. In India, lymph node TB(LNTB) was more common among EPTB cases. Bangladesh reported a high prevalence of EPTB involving lymph node, pleura, and abdomen, while Afghanistan had a higher prevalence of forms such as LNTB and tuberculous meningitis. Conclusion:In conclusion, the prevalence of EPTB in Pakistan, Afghanistan, India, and Bangladesh is alarmingly high and negatively impacts population health.Effective measures are needed for treatment and management of this condition,

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Section: Susceptibility Of Extrapulmonary Tb In South Asiansmentioning

confidence: 99%

Section: Susceptibility Of Extrapulmonary Tb In South Asiansmentioning

confidence: 99%

Better understanding extrapulmonary tuberculosis: A scoping review of public health impact in Pakistan, Afghanistan, India, and Bangladesh

Jawed

Tharwani

Siddiqui

et al. 2023

Health Science Reports

View full text Add to dashboard Cite

show abstract

“…1 Nearly 85% of the new global TB cases were diagnosed in sub-Saharan Africa and South Asia. Para-aminosalicylic acid (PAS), isoniazid (INH), pyrazinamide (PZA), 2,3 cycloserine, ethionamide, rifampicin, and ethambutol have been used as chemotherapy drugs for tuberculosis since the 1940s. However, multidrug-resistant tuberculosis has demonstrated the need for new anti-TB agents.…”

Section: Introductionmentioning

confidence: 99%

A computational study of Di-substituted 1,2,3-triazole derivatives as potential drug candidates against Mycobacterium tuberculosis: 3D-QSAR, molecular docking, molecular dynamics, and ADMETox

et al. 2023

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Tuberculosis burden in immigrants and natives, adults and children, in Tuscany between 2000–2018

Cited by 2 publications

References 53 publications

Better understanding extrapulmonary tuberculosis: A scoping review of public health impact in Pakistan, Afghanistan, India, and Bangladesh

Better understanding extrapulmonary tuberculosis: A scoping review of public health impact in Pakistan, Afghanistan, India, and Bangladesh

A computational study of Di-substituted 1,2,3-triazole derivatives as potential drug candidates against Mycobacterium tuberculosis: 3D-QSAR, molecular docking, molecular dynamics, and ADMETox

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