Tuberculosis Predictive Index for Type 2 Diabetes Mellitus Patients Based on Biological, Social, Housing Environment, and Psychological Well-Being Factors

Isfandiari, Muhammad Atoillah; Wahyuni, Chatarina Umbul; Pranoto, Agung

doi:10.3390/healthcare10050872

Cited by 3 publications

(2 citation statements)

References 26 publications

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“…However, the results showed that there is no obvious spatial heterogeneity in the four risk factors (age, hypertension, dyslipidemia, and smoking history). This might be because this study did not incorporate socioeconomic and environmental factors into the study [ 64 , 65 ].…”

Section: Discussionmentioning

confidence: 99%

Spatiotemporal Analysis and Risk Assessment Model Research of Diabetes among People over 45 Years Old in China

Wang

Dong

Yang

2022

IJERPH

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Diabetes, which is a chronic disease with a high prevalence in people over 45 years old in China, is a public health issue of global concern. In order to explore the spatiotemporal patterns of diabetes among people over 45 years old in China, to find out diabetes risk factors, and to assess its risk, we used spatial autocorrelation, spatiotemporal cluster analysis, binary logistic regression, and a random forest model in this study. The results of the spatial autocorrelation analysis and the spatiotemporal clustering analysis showed that diabetes patients are mainly clustered near the Beijing–Tianjin–Hebei region, and that the prevalence of diabetes clusters is waning. Age, hypertension, dyslipidemia, and smoking history were all diabetes risk factors (p < 0.05), but the spatial heterogeneity of these factors was weak. Compared with the binary logistic regression model, the random forest model showed better accuracy in assessing diabetes risk. According to the assessment risk map generated by the random forest model, the northeast region and the Beijing–Tianjin–Hebei region are high-risk areas for diabetes.

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Section: Discussionmentioning

confidence: 99%

Spatiotemporal Analysis and Risk Assessment Model Research of Diabetes among People over 45 Years Old in China

Wang

Dong

Yang

2022

IJERPH

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“…The pleiotropy test assesses whether multiple instrumental variables exhibit horizontal pleiotropy, commonly indicated by the intercept term in MR-Egger regression. A significant deviation of the intercept term from zero suggests the presence of horizontal pleiotropy [ 16 ]. The leave-one-out sensitivity test calculates the MR result with one instrumental variable excluded at a time [ 17 ].…”

Section: Methodsmentioning

confidence: 99%

The causal relationship between COVID-19 and seventeen common digestive diseases: a two-sample, multivariable Mendelian randomization study

Wang,

Zhou,

Zhang

et al. 2023

Hum Genomics

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Objectives In clinical practice, digestive symptoms such as nausea, vomiting are frequently observed in COVID-19 patients. However, the causal relationship between COVID-19 and digestive diseases remains unclear. Methods We extracted single nucleotide polymorphisms associated with the severity of COVID-19 from summary data of genome-wide association studies. Summary statistics of common digestive diseases were primarily obtained from the UK Biobank study and the FinnGen study. Two-sample Mendelian randomization analyses were then conducted using the inverse variance-weighted (IVW), Mendelian randomization-Egger regression (MR Egger), weighted median estimation, weighted mode, and simple mode methods. IVW served as the primary analysis method, and Multivariable Mendelian randomization analysis was employed to explore the mediating effect of body mass index (BMI) and type 2 diabetes. Results MR analysis showed that a causal association between SARS-CoV-2 infection (OR = 1.09, 95% CI 1.01–1.18, P = 0.03), severe COVID-19 (OR = 1.02, 95% CI 1.00–1.04, P = 0.02), and COVID-19 hospitalization (OR = 1.04, 95% CI 1.01–1.06, P = 0.01) with gastroesophageal reflux disease (GERD). Mediation analysis indicated that body mass index (BMI) served as the primary mediating variable in the causal relationship between SARS-CoV-2 infection and GERD, with BMI mediating 36% (95% CI 20–53%) of the effect. Conclusions We found a causal relationship between SARS-CoV-2 infection and gastroesophageal reflux disease. Furthermore, we found that the causal relationship between SARS-CoV-2 infection and GERD is mainly mediated by BMI.

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Transmission rate factors among tuberculosis patients in West Kalimantan, Indonesia

Yulanda,

Martadi,

Ligita

et al. 2023

Healthc Low-resour S

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Tuberculosis is a critical issue in a community, and the rising number of cases can be attributed the development and evolution of the bacteria responsible. As part of independent nursing actions, educational intervention is a solution to improve prevention and treatment success at the family and community levels. This study aimed to determine the factors for Tuberculosis transmission. This research was a correlation study with a cross-sectional design, involving a sample of 100 participants selected through purposive sampling. Independent variables for the present study include age, gender, occupation, diabetes record, body mass index (BMI), and level of knowledge. Meanwhile, the dependent variable in this study is the risk of transmission. This observation used a questionnaire with chi-square and logistic regression analysis. The result showed that families with a thin body mass index had a lower likelihood of carrying out infectious behavior (p=0.000). Most respondents have a high level of knowledge and a low potential for infectious behavior. In fact, a good education system, it will allow someone to be independently trained to change behaviors and attitudes for the better.

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Tuberculosis Predictive Index for Type 2 Diabetes Mellitus Patients Based on Biological, Social, Housing Environment, and Psychological Well-Being Factors

Cited by 3 publications

References 26 publications

Spatiotemporal Analysis and Risk Assessment Model Research of Diabetes among People over 45 Years Old in China

Spatiotemporal Analysis and Risk Assessment Model Research of Diabetes among People over 45 Years Old in China

The causal relationship between COVID-19 and seventeen common digestive diseases: a two-sample, multivariable Mendelian randomization study

Transmission rate factors among tuberculosis patients in West Kalimantan, Indonesia

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