Tuberculous brain abscess in a child with tetralogy of Fallot

Abstract

Letters to Editor include: Maculopapular rash, Þ xed drug eruption (FDE), erythema multiforme (EM), toxic epidermal necrolysis (TEN), Stevens-Johnson syndrome (SJS), urticaria, and erythroderma. [1] Maculopapular rash is the most common skin lesion with AEDs. The serious skin allergies include SJS and TEN. Skin allergies have been described more often in patients receiving carbamazepine, phenytoin and lamotrigine. [2] Cutaneous eruptions are least with valproate compounds. Review of English literature showed only report of two cases of psoriasiform eruption with valproate. [3,4] Drug treatment may result in exacerbation of pre-existing psoriasis, can induce psoriatic lesions on clinically uninvolved skin in patients with psoriasis, or can precipitate the disease in predisposed individuals. [5] Our patient had no past or family history of psoriasis and no relapse of lesions at one year of follow up, thus suggesting that the psoriasiform eruption in him were probably related to valproate treatment. The knowledge of the drugs that may induce, trigger, or exacerbate psoriasis, is of importance in clinical practice. The drugs that may induce psoriasis include lithium, beta-adrenergic antagonists, antimalarial, non-steroidal anti-inflammatory drugs (NSAIDs) and rarely tetracycline. [6] To this list we should add valproate and valproate should be used with caution in individuals with pre-existing psoriasis.

CNS tuberculoma in patient with tetralogy of fallot: A case report

“…Brain abscess is a rare complication occurring in almost 11% of congenital cyanotic heart disease and among them it is most commonly seen in the TOF. 6 Tubercular abscess occurs mostly in developing countries where there is poor sanitation, lack of medical facilities, and risk of tuberculosis infection is high. 7 The overall incidence of brain abscess in patients with congenital cyanotic heart disease is decreasing due to early diagnosis and early surgical interventions.…”

“…The common complications of TOF include delayed developmental milestones, secondary polycythemia, and infective endocarditis. Brain abscess is a rare complication occurring in almost 11% of congenital cyanotic heart disease and among them it is most commonly seen in the TOF 6 . Tubercular abscess occurs mostly in developing countries where there is poor sanitation, lack of medical facilities, and risk of tuberculosis infection is high 7 .…”

Absceso cerebral: diagnóstico, manejo, complicaciones y pronóstico

“…Al igual que los inmunosuprimidos estos pacientes tienen riesgo de presentar Abscesos secundario a Mycobacterium Tuberculosis 26 . -Inmunosuprimidos: Especies de Nocardia, Listeria, Toxoplasma Gondii, Aspergillus, Cryptococcus Neoformans, Candida, Taenia Solium 27 , Micobacterias 28 . Los pacientes inmunosuprimidos adicionalmente corren el riesgo de presentar feohifomicosis cerebral, que por lo general se manifiesta como absceso cerebral único 29,30 .…”

Absceso cerebral: diagnóstico, manejo, complicaciones y pronóstico

“…Al igual que los inmunosuprimidos estos pacientes tienen riesgo de presentar Abscesos secundario a Mycobacterium Tuberculosis 26 . -Inmunodeprimidos: Especies de Nocardia, Listeria, Toxoplasma Gondii, Aspergillus, Cryptococcus Neoformans, Candida, Taenia Solium 27 , Micobacterias 28 . Los pacientes inmunosuprimidos adicionalmente corren el riesgo de presentar feohifomicosis cerebral, que por lo general se manifiesta como absceso cerebral único 29,30 .…”