Tubulo-squamous Vaginal Polyp With Basaloid Epithelial Differentiation

Stewart, Colin J.R.

doi:10.1097/pgp.0b013e3181a9cd86

Cited by 20 publications

(11 citation statements)

References 8 publications

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“…7 Few additional cases have been described, 2,11 although it has been suggested that similar cases had been earlier reported as mixed tumor of the vagina. 1,6,7 In fact,1 of our cases was originally classified as such.…”

Section: Discussionmentioning

confidence: 95%

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Prostatic-type Tissue in the Lower Female Genital Tract: A Morphologic Spectrum, Including Vaginal Tubulosquamous Polyp, Adenomyomatous Hyperplasia of Paraurethral Skene Glands (Female Prostate), and Ectopic Lesion in the Vulva

Kazakov¹,

Stewart

Kacerovská³

et al. 2010

American Journal of Surgical Pathology

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The investigators report a series of prostatic-type lesions occurring in the lower female genital tract. The cases included a 4.5-cm mass representing hyperplasia of the glandular and stromal tissue of paraurethral Skene gland, a small ectopic prostatic lesion in the vulva, and 4 tubulosquamous vaginal polyps. All lesions were immunopositive for prostate-specific antigen and/or prostatic acid phosphatase. A brief discussion of the earlier published material is included.

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Section: Discussionmentioning

confidence: 95%

“…In 1 of these cases, there were also basaloid cells with palisading at the periphery of the nodules, identical in appearance to those earlier reported in a vaginal tubulosquamous polyp by one of us (CJS). 11 One case also showed focal intracytoplasmic granular cell change (Fig. 4A).…”

Section: Cases 3 To 6: Tubulosquamous Polyps Of the Vagina With Focalmentioning

confidence: 96%

Prostatic-type Tissue in the Lower Female Genital Tract: A Morphologic Spectrum, Including Vaginal Tubulosquamous Polyp, Adenomyomatous Hyperplasia of Paraurethral Skene Glands (Female Prostate), and Ectopic Lesion in the Vulva

Kazakov¹,

Stewart

Kacerovská³

et al. 2010

American Journal of Surgical Pathology

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“…The glands are usually positive for PAP and/or PSA. Vaginal polyps with the glands were reported as TSPs (1)(2)(3)(4)(5)(6). McCluggage and Young (3), who initially described 10 cases of TSPs, speculated a possible origin from ectopic prostate or Skene glands.…”

Section: Discussionmentioning

confidence: 97%

“…In the vagina, these lesions have generally taken the form of a polyp, termed tubulosquamous polyp (TSP), which may be derived from Skene glands (1)(2)(3)(4)(5)(6). In the cervix, this has been termed ectopic prostatic tissue (7)(8)(9)(10)(11).…”

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confidence: 98%

Uterine Cervical Tubulosquamous Polyp Resembling a Penis

Fukunaga

2013

International Journal of Gynecological Pathology

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This case report describes a tubulosquamous polyp resembling a penis in the uterine cervix. A 34-yr-old, gravida 0, para 0, woman showed an 18 × 8 × 5 mm polypoid lesion in the uterine ectocervix. The polyp had a penis-like appearance; the tip looked like glans penis and the middle portion resembled the shaft of the penis. Its surface was covered by squamous epithelium, and tissues resembling those of a urethra, corpus spongiosum penis, and external orifice urethra were observed. Foreskin-like tissues were also observed, although a corpus cavernosum penis was not seen. Skene glands and Cowper glands were also observed. Immunohistochemically, Skene glands and the urethra-like epithelium were focally positive for prostate-specific antigen and/or prostatic acid proteins. Histologically and immunohistochemically, the polypoid lesion overlapped with a tubulosquamous polyp of the vagina and ectopic prostatic tissue of the uterine cervix and encompassed these lesions in the lower female genital tract. The most likely theory of histogenesis is a developmental anomaly and misplacement of Skene glands.

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“…Although our case was negative with PSA and PSAP, some of the tubulo-squamous polyps reported in the literature, showed immunoreactivity with PSA and/or PSAP (1,2). Thus, it is suggested that these lesions are originated from paraurethral Skene glands (the female equivalent of prostatic glands in the male) or ectopic prostate tissue (2,6). However, none of these theories has been proved to date.…”

Section: Discussionmentioning

confidence: 99%

A rare lesion of the vagina: tubulo-squamous polyp

Şahin¹,

Yılmaz²,

Erdem³

2014

Gaziantep Med J

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Vaginal polyps are uncommon and consist of a heterogeneous group of lesions. Most of vaginal polypoid lesions are fibroepithelial polyps. However, a variety of lesions (leiomyoma, superficial myofibroblastoma of the lower female genital tract, rhabdomyoma, and embryonal rhabdomyosarcoma etc.) may present macroscopically as a polypoid mass. Tubulo-squamous polyp of the vagina is a rare benign lesion that has been described recently. Histologically, it is characterized by both epithelial and mesenchymal component, consisting of squamous nests and tubules, embedded in a fibrous stroma. Focal immunoreactivity for prostatespecific antigen (PSA) and/or prostatic acid phosphatase (PSAP) may be observed in some lesions, supporting the possibility that it originates from paraurethral Skene's glands. Herein, we report a 60-year-old female with a tubulo-squamous polyp of the vagina. A brief review of the literature on this novel entity is also provided. Keywords: Polyps; tubulo-squamous; vagina ÖzetVajinal polipler nadirdir ve heterojen bir grup lezyondan oluşmaktadır. Fibroepitelyal polipler en sık vajinal polipoid lezyonlardır. Ancak çok çeşitli lezyonlar (leiomyom, alt kadın genital sistemin yüzeyel myofibroblastomu, rabdomyom ve embryonel rabdomyosarkom vs.) makroskopik olarak vajinal polipoid kitle şeklinde ortaya çıkabilmektedir. Tübüloskuamoz polip ise vajinanın yakın zamanda tanımlanan nadir bir benign lezyonudur. Histolojik olarak fibröz stroma içerisinde skuamoz adalar ve tübüllerden oluşan epitelyal ve mezenkimal komponentler ile karakterlidir. Bazı lezyonlarda paraurethral Skene bezlerinden köken alabileceğini destekleyen prostat spesifik antijen (PSA) ve/veya prostatik asit fosfataz (PSAP) ile fokal immünreaktivite saptanabilmektedir. Biz burada 60 yaşında kadın hastaya ait bir vajinal tübüloskuamoz polibi sunmaktayız. Ayrıca bu yeni antite ile ilgili kısa bir literatür özeti de verilmiştir.

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Tubulo-squamous Vaginal Polyp With Basaloid Epithelial Differentiation

Cited by 20 publications

References 8 publications

Prostatic-type Tissue in the Lower Female Genital Tract: A Morphologic Spectrum, Including Vaginal Tubulosquamous Polyp, Adenomyomatous Hyperplasia of Paraurethral Skene Glands (Female Prostate), and Ectopic Lesion in the Vulva

Prostatic-type Tissue in the Lower Female Genital Tract: A Morphologic Spectrum, Including Vaginal Tubulosquamous Polyp, Adenomyomatous Hyperplasia of Paraurethral Skene Glands (Female Prostate), and Ectopic Lesion in the Vulva

Uterine Cervical Tubulosquamous Polyp Resembling a Penis

A rare lesion of the vagina: tubulo-squamous polyp

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