Tumor Ablation: Common Modalities and General Practices

Knavel, Erica M.; Brace, Christopher L.

doi:10.1053/j.tvir.2013.08.002

Cited by 282 publications

(237 citation statements)

References 82 publications

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“…Slight temperature variance in tissue-laser interaction has been reported depending on tissue type, with tumor cells generally more sensitive to heating than normal cells. This is thought be due to variations in oxygen levels and pH [4]. To our knowledge, temperature sensitivity in different tissue type has yet to be explored in epileptic tissues.…”

Section: Principals Of Littmentioning

confidence: 99%

Magnetic Resonance Imaging-Guided Laser Interstitial Thermal Therapy for Treatment of Drug-Resistant Epilepsy

Kang

Sperling

2017

Neurotherapeutics

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Surgery is the most effective treatment for drug-resistant epilepsy. Long-term studies demonstrate that about 60% to 80% of patients become seizure-free after anterior temporal lobectomy and a majority of patients (about 95%) report significant seizure reduction after surgery. In the last few years, there has been significant advances in minimally invasive surgical techniques to treat drug-resistant epilepsy. These minimally invasive procedures have significant advantages over open surgery in that they produce less immediate discomfort and disability, while allowing for greater preservation of functional tissue. Laser interstitial thermal therapy (LiTT) is an example of such a procedure. Recent advances in imaging, surgical navigation, and real-time thermal monitoring have made LiTT safer and easier to implement, offering an effective and powerful neurosurgical tool for drug-resistant epilepsy. This article will review the technical considerations, uses, and potential future directions for LiTT in drugresistant epilepsy.

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Section: Principals Of Littmentioning

confidence: 99%

Magnetic Resonance Imaging-Guided Laser Interstitial Thermal Therapy for Treatment of Drug-Resistant Epilepsy

Kang

Sperling

2017

Neurotherapeutics

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“…Multiple studies proved that multiple applicators use can be more efficient where it is applicable. It can increase the effectiveness of the treatment in some cases [17,[48][49][50].…”

Section: Thermal Ablation Optionsmentioning

confidence: 99%

“…Finally, the carbonization and the pyrolyze phenomena appear. Figure 3 explains the various phenomena depending on the temperature amplitude and the time exposure [17].…”

Section: Death Process Of Cells With Temperaturementioning

confidence: 99%

“…The common frequencies used in RFA vary in the range of 375-500 KHz. This modality has been widely deployed and practiced to treat cancer in many cases: liver, breast, brain [8,15,17,18,49,50]. It consists of transforming the body on a simple electrical circuit that produces a resistive heating in the surrounding tissue of the used probe [17].…”

Section: Radio Frequency Ablation (Rfa)mentioning

confidence: 99%

“…Several energy sources have been used to overheat the tissue with different approaches, invasive, minimally invasive and superficial. It includes RF, MW, LASER, US and gas for cooling in Cryotherapy [1,16,17].…”

Section: Thermal Ablation Optionsmentioning

confidence: 99%

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Thermal Therapy Modalities for Cancer Treatment: A Review and Future Perspectives

Mellal¹,

Oukaira²,

Kengene³

et al. 2017

Appl Sci Res Rev

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Assessment of Radiofrequency Ablation for Papillary Microcarcinoma of the Thyroid

Dijk

Coerts

Gunput

et al. 2022

JAMA Otolaryngol Head Neck Surg

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IMPORTANCE Papillary microcarcinomas of the thyroid (mPTCs) account for an increasing proportion of thyroid cancers in past decades. The use of radiofrequency ablation (RFA) has been investigated as an alternative to surgery. The effectiveness and safety of RFA has yet to be determined. OBJECTIVE To evaluate the effectiveness and safety of RFA for low-risk mPTC. DATA SOURCES Embase, MEDLINE via Ovid, Web of Science Core Collection, Cochrane Central Register of Controlled Trials, and the top 100 references of Google Scholar were searched from inception to May 28, 2021. STUDY SELECTION Articles reporting on adult patients with mPTC treated with RFA were included. Studies that involved patients with pre-ablation lymph node or distant metastases, recurrence of disease, or extrathyroidal extension were excluded. Final article selection was conducted by multiple reviewers based on consensus. The proportion of eligible articles was 1%.DATA EXTRACTION AND SYNTHESIS This meta-analysis was conducted in accordance with the MOOSE guidelines. Random and fixed-effect models were applied to obtain pooled proportions and 95% CIs. MAIN OUTCOMES AND MEASURESThe primary outcome was the complete disappearance rate of mPTC. Secondary outcomes were tumor progression and complications. RESULTSFifteen studies were included in this meta-analysis. A total of 1770 patients (1379 women [77.9%]; mean [SD] age, 45.4 [11.4] years; age range, 42.5-66.0 years) with 1822 tumors were treated with RFA; 49 tumors underwent 1 additional RFA session and 1 tumor underwent 2 additional RFA sessions. Mean (SD) follow-up time was 33.0 (11.4) months (range, 6-131 months). The pooled complete disappearance rate at the end of follow-up was 79% (95% CI, 65%-94%). The overall tumor progression rate was 1.5% (n = 26 patients), local residual mPTC in the ablation area was found in 7 tumors (0.4%), new mPTC in the thyroid was found in 15 patients (0.9%), and 4 patients (0.2%) developed lymph node metastases during follow-up. No distant metastases were detected. Three major complications occurred (2 voice changes lasting >2 months and 1 cardiac arrhythmia). Minor complications were described in 45 patients. CONCLUSIONS AND RELEVANCEThe findings of this systematic review and meta-analysis suggest that RFA is a safe and efficient method to treat selected low-risk mPTCs. Radiofrequency ablation could be envisioned as step-up treatment after local tumor growth under active surveillance for an mPTC or initial treatment in patients with mPTCs with anxiety about active surveillance.

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Tumor Ablation: Common Modalities and General Practices

Cited by 282 publications

References 82 publications

Magnetic Resonance Imaging-Guided Laser Interstitial Thermal Therapy for Treatment of Drug-Resistant Epilepsy

Magnetic Resonance Imaging-Guided Laser Interstitial Thermal Therapy for Treatment of Drug-Resistant Epilepsy

Thermal Therapy Modalities for Cancer Treatment: A Review and Future Perspectives

Assessment of Radiofrequency Ablation for Papillary Microcarcinoma of the Thyroid

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