Tumor Microenvironment Modulation by Cancer-Derived Extracellular Vesicles
Artem Ten,
Vadim Kumeiko,
Vladislav Farniev
et al.
Abstract:The tumor microenvironment (TME) plays an important role in the process of tumorigenesis, regulating the growth, metabolism, proliferation, and invasion of cancer cells, as well as contributing to tumor resistance to the conventional chemoradiotherapies. Several types of cells with relatively stable phenotypes have been identified within the TME, including cancer-associated fibroblasts (CAFs), tumor-associated macrophages (TAMs), neutrophils, and natural killer (NK) cells, which have been shown to modulate can… Show more
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