Tumor microtubes: A new potential therapeutic target for high-grade gliomas
Yunzhu Guo,
Yangxin Li,
Peng Su
et al.
Abstract:High-grade infiltrating gliomas are highly aggressive and fatal brain tumors that present significant challenges for research and treatment due to their complex microenvironment and tissue structure. Recent discovery of tumor microtubes (TMs) has provided new insights into how high-grade gliomas develop in the brain and resist treatment. TMs are unique, ultra-long, and highly functional membrane protrusions that form multicellular networks and play crucial roles in glioma invasiveness, drug resistance, recurre… Show more
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