Tumor Syndromes That Include Bone Tumors

Gnoli, Maria; Ponti, Francesca; Sangiorgi, Luca

doi:10.1016/j.path.2017.04.009

Cited by 7 publications

(2 citation statements)

References 76 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, additional clinical features unrelated to the neoplasm can be a hallmark of specific genetic syndromes. 222 Massively parallel sequencingbased studies will continue to widen the spectrum of known predisposing genetic variants among patients with soft tissue and bone tumors.…”

Section: Genetic Tumor Syndromes Of Soft Tissue and Bonementioning

confidence: 99%

“…Generally, the occurrence of bilateral, multifocal, or metachronous neoplasms and specific histopathologic findings can suggest a genetic predisposition syndrome. Moreover, additional clinical features unrelated to the neoplasm can be a hallmark of specific genetic syndromes 222. Massively parallel sequencing-based studies will continue to widen the spectrum of known predisposing genetic variants among patients with soft tissue and bone tumors.…”

Section: Genetic Tumor Syndromes Of Soft Tissue and Bonementioning

confidence: 99%

See 1 more Smart Citation

The 2020 WHO Classification of Tumors of Bone: An Updated Review

Choi

2021

Advances in Anatomic Pathology

198

109

View full text Add to dashboard Cite

Bone tumors are a rare and heterogeneous group of neoplasms that occur in the bone. The diversity and considerable morphologic overlap of bone tumors with other mesenchymal and nonmesenchymal bone lesions can complicate diagnosis. Accurate histologic diagnosis is crucial for appropriate management and prognostication. Since the publication of the fourth edition of the World Health Organization (WHO) classification of tumors of soft tissue and bone in 2013, significant advances have been made in our understanding of bone tumor molecular biology, classification, prognostication, and treatment. Detection of tumor-specific molecular alterations can facilitate the accurate diagnosis of histologically challenging cases. The fifth edition of the 2020 WHO classification of tumors of soft tissue and bone tumors provides an updated classification scheme and essential diagnostic criteria for bone tumors. Herein, we summarize these updates, focusing on major changes in each category of bone tumor, the newly described tumor entities and subtypes of existing tumor types, and newly described molecular and genetic data.

show abstract

Section: Genetic Tumor Syndromes Of Soft Tissue and Bonementioning

confidence: 99%

Section: Genetic Tumor Syndromes Of Soft Tissue and Bonementioning

confidence: 99%