Tumor with slow‑developing and recurring lumps of the external ear with skull base and lung metastasis: A case report

Abstract

The present case report describes a rare case of recurring lumps on the external ear in a 46-year-old Chinese male with a history of >10 years, who presented with large irregular red lumps on the right temple and with lung and skull base metastasis. The patient had a lesion in the right auricle and experienced recurrence following surgical resection. A thorough systemic evaluation revealed no other obvious abnormalities. The patient was diagnosed with adenoid cystic carcinoma (ACC), a slow-growing form of high-grade adenocarcinoma, and refused any further treatment at the present hospital (The First Affiliated Hospital of Army Medical University). At 2 years post-follow-up, the patient had become more frail but was in good spirits. The present study indicated that ACC is a low-grade and commonly slow-developing malignancy that primarily arises from a salivary gland, with recurring and metastatic characteristics.

Novel pyroptosis-associated genes signature for predicting the prognosis of sarcoma and validation

“…Histological biopsy is the most authoritative standard for the diagnosis of Sarcoma [ 34 , 35 ]. The main therapeutic methods are radiation therapy and surgery [ 36 ], and there are still no proven target drugs for sarcomas. Up to now, the mechanism of sarcomas is still poorly understood, which is the main obstacle to the development of specific targeted drugs.…”