The laser performance of coumarin 440 (C440) and coumarin 460 (C460) mixture is studied. The mixture dyes demonstrated broader and more efficient tuning curves compared with those of coumarin 440 and coumarin 460. A wide tuning range from 421 nm to 482 nm is achieved. The highest conversion efficiency of 12.2% is obtained at 453 nm. Comparing with the efficiencies of individual dye C440 and C460, which are ∼5%, the tuning range and the conversion efficiency of the coumarin 440 (C440) and coumarin 460 (C460) mixture are the best under the same condition so far. All our results indicate that high laser performance can be achieved using the co-doped laser dyes of coumarin 440 and coumarin 460.