2020
DOI: 10.26434/chemrxiv.12924686.v1
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Tuneable Thiol-Ene Photo-Crosslinked Chitosan-Based Hydrogels for Biomedical Applications

Abstract: <p>Access to biocompatible hydrogels with tuneable properties is of great interest. Here we report the practical synthesis and characterisation of a series of photo-crosslinked chitosan hydrogels from norbornene-functionalised chitosan (CS-nb) and various thiolated crosslinkers. The resulting materials were characterised by NMR, swelling ratio, rheology, SEM and SANS. The new hydrogels exhibit pH- and salt-dependent swelling whilst the macro- and microscale properties can be modulated by the choice and d… Show more

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