Twisted intramolecular charge transfer, nonlinear optical, antibacterial activity, and DFT analysis of ultrasound processed (E)-N′-(4-isopropylbenzylidene)nicotinohydrazide

Complexation behavior of copper and zinc divalent ions towards diisatin malonyl dihydrazone ligand with biological and catalytic assessments

“…At the ambient temperature, the mole conducted strength of CuLm and ZnLm concentered solution of 1.0 Â 10 À3 mol dm À3 in N,N-dimethylformamide (DMF) and dimethyl sulfoxide was evaluated within the Jenway conductivity meter. At 25 C and in dimethyl sulfoxide (DMSO)-d 6 , the nuclear magnetic resonance spectra of 1 H protons and 13 C nuclei for H 2 Lm and ZnLm were accomplished using the FT-NMR Bruker multinuclear spectrophotometric instrument of the ARX400 model. The magnetic fields of the 13 C nuclei 1 H protons were applied at 100.6 and 400.1 MHz, respectively.…”

“…At 25 C and in dimethyl sulfoxide (DMSO)-d 6 , the nuclear magnetic resonance spectra of 1 H protons and 13 C nuclei for H 2 Lm and ZnLm were accomplished using the FT-NMR Bruker multinuclear spectrophotometric instrument of the ARX400 model. The magnetic fields of the 13 C nuclei 1 H protons were applied at 100.6 and 400.1 MHz, respectively. At 25 C, Fourier-transform infrared (FT-IR) spectroscopy for the solid phase of H 2 Lm, CuLm, and ZnLm (as solid samples) was examined with an Agilent Technology instrument of FT-IR spectrophotometer (Cary-630 model).…”

“…The tautomeric 1 HNMR spectra of the dienolic form are δ = 12.58 (s, NH), 11.22 (s, NH), and 3.56 ppm (s, 2H, CH 2 , malonyl). 13 CNMR spectra of H 2 Lm: δ = 164.94 (C q , C=O), 158.63 (C q , C=O), 157.91 (C q , C=N), 150.92 (CH 2 , malonyl), 126.57 (C q ), 122.16 (CH), and 115.69 ppm (CH) (Figure S2).…”

“…9 From the literature survey, the less toxicity and harmless side effects of some transition metals, 10,11 such as Co, Zn, Cu, Ni, and V, motivated many researchers to publish progressed works concerning the considerable biological activity, such as, of Cu(I/II)-coordination compounds of various backbone ligands, as reported currently. 12 The antibacterial reactivity of new constructed mononuclear vanadium (III) complexes of hydrazide-hydrazone ligands was studied in detail with comparable theoretical essays, which were published by Meenatchi et al 13 Azomethine and imine chelates of VO 2+ , Zn 2+ , and Cu 2+ have been employed against DNA for the evaluation of their interacting ability, which represented currently referring to the nature of such interacting binding. 14 The role of the coordinate hydrazone chelates, as bioorganoligands, was discovered in vitro cytotoxicity examination for the dinuclear complexes of dioxo-vanadium (V) ions, which was reported at present by Choudhury et al 15 The biological importance of such hydrazone ligands in their coordinated forms and their relationship with vanadium and molybdenum ions, as pyridoxal derivatives, was examined and documented by Avecilla et al 16 The most versatile transition metals are copper and zinc (the most abundant and cheap ones in the earth's crust) with structural and chemical interests for various bio-applicable purposes.…”

Effect of Cu+/2+ ions on the biological activity of their bis‐oxalyldihydrazone complexes: ctDNA interaction, antimicrobial and anticancer action

“…7 Interestingly, the more lipophilic character and high Lewis acidity of CuL1 (with Cu + ion) compared with that of CuL2 (Cu 2+ ion), due to the low charge of Cu + ion, could further advance its action with ctDNA over that of CuL2. 53 Viscosity studies From the UV-vis spectroscopic studies for the interacting mode between alternative concentrated solutions of ctDNA with H 2 Lx, CuL1, and CuL2 in DMSO encouraged us to study their interacting reactivity towards ctDNA through the increased solution of ctDNA viscosity. For the mixed solutions of ctDNA and H 2 Lx, CuL1, or CuL2, the enhanced viscosity of ctDNA solution was detected referring to their progressed interacting action towards ctDNA.…”