Two biflavonoids from Daphne acutiloba

Taniguchi, Masahiko; Fujiwara, Akiko; K, Baba; Wang, Nian-He

doi:10.1016/s0031-9422(98)00181-2

Cited by 28 publications

(21 citation statements)

References 2 publications

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“…By comparing the physical and spectroscopic data with those in literatures, 13 known biflavonoids were identified as: daphnodorin A (3), 6,7) daphnodorin B (4), 6,7) daphnodorin C (5), 7,8) daphnodorin I (6), 9) daphnodorin J (7), 10) a mixture of daphnodorins M and N (8), 11) dihydrodaphnodorin B (9), 10) wikstrol A (10), 12) wikstrol B (11), 12) genkwanol B (12), 13) genkwanol C (13), 14) neochamaejasmin B (14), 15) isoneochamaejasminin A (15). 16) Compound 1 ( Fig.…”

Section: Notesmentioning

confidence: 99%

Biflavonoids from Daphne feddei and Their Inhibitory Activities against Nitric Oxide Production

Liang

Tang

Shen

et al. 2008

CHEMICAL & PHARMACEUTICAL BULLETIN

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Bioassay-directed fractionation led to the isolation of two new biflavonoids and 13 known biflavonoids from a sample of the dried stem barks of Daphne feddei. The structures of compounds 1 and 2 were elucidated as 2؆-methoxy-daphnodorin C (1) and 2؆-methoxy-2-epi-daphnodorin C (2) on the basis of detailed spectroscopic analysis and X-ray crystallography. All 15 biflavonoids were tested for inhibitory activities against lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 macrophages. Compounds 1, 2, 8, 10, 14 and 15 showed varying degrees of inhibitory activities against the production of NO in tested concentration of 25, 50, 75 and 100 m mg/ml.

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Section: Notesmentioning

confidence: 99%

Biflavonoids from Daphne feddei and Their Inhibitory Activities against Nitric Oxide Production

Liang

Tang

Shen

et al. 2008

CHEMICAL & PHARMACEUTICAL BULLETIN

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“…The root and the bark of the D. acutiloba plant is used in traditional Chinese medicine under the name "jin yao dai" to treat bruises and scrofula (71).…”

Section: Th E Plant Species Of the Genus Daphne: Pharmacology Screenimentioning

confidence: 99%

Plants from The Genus Daphne: A Review of its Traditional Uses, Phytochemistry, Biological and Pharmacological Activity

Sovrlić

Manojlović

2017

Serbian Journal of Experimental and Clinical Research

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“…Daphne species are proposed in cancer treatment since the prehistoric ages (Kupchan and Baxter 1974). Some Daphne species, such as D. genkwa and D. acutiloba , are used in traditional Chinese medicine for various cancer types treatment (Taniguchi et al . 1998; Zhan et al .…”

Section: Introductionmentioning

confidence: 99%

A Study on Antioxidant Capacities and Fatty Acid Compositions of TwoDaphneSpecies from Turkey: New Sources of Antioxidants and Essential Fatty Acids

Zengin

Arkan

Aktümsek

et al. 2012

Journal of Food Biochemistry

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Daphne (Thymealaceae) species have been widely used in traditional Anatolian medicine. The antioxidant capacity and fatty acid composition of two Daphne taxa (D. oleoides subsp. oleoides and D. serica) were studied. The antioxidant properties of four solvent extracts of Daphne species were assessed using different chemical assays including phosphomolybdate assay, free radical-scavenging assay, b-carotene/ linoleic acid test system, ferric and cupric reducing power. The total phenolic and flavonoid content of the extracts also were determined. Ethyl acetate, methanol and ethanol extracts obtained from the Daphne species possess strong antioxidant potential. Polyunsaturated fatty acids in the studied oils were the highest level in the fatty acid components. Essential fatty acids accounted for 27.46-45.31% of total fatty acids. These results indicated that the extracts of studied Daphne taxa can be exploited as a source of natural antioxidants and essential fatty acids in pharmacological and food industry. PRACTICAL APPLICATIONSMembers of the genus Daphne have been of great interest owing to their excellent medicinal value. The aim of this study was to discuss antioxidant properties of different solvent extracts and fatty acid composition of two Daphne species. Different chemical assays were performed to antioxidant capacities of the extracts. The results of our in vitro study suggested that the Daphne extracts could be considered as a source of natural antioxidants and essential fatty acids for medicinal and commercial uses.

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Two biflavonoids from Daphne acutiloba

Cited by 28 publications

References 2 publications

Biflavonoids from Daphne feddei and Their Inhibitory Activities against Nitric Oxide Production

Biflavonoids from Daphne feddei and Their Inhibitory Activities against Nitric Oxide Production

Plants from The Genus Daphne: A Review of its Traditional Uses, Phytochemistry, Biological and Pharmacological Activity

A Study on Antioxidant Capacities and Fatty Acid Compositions of TwoDaphneSpecies from Turkey: New Sources of Antioxidants and Essential Fatty Acids

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