Two Cases of Spontaneous Filtering Blebs, One Idiopathic and One Associated With Terrien Marginal Degeneration

Munro, Monique; McWhae, John A.; Romanchuk, Kenneth; Crichton, Andrew; Carter, Gordon; Ball, Arlene

doi:10.1097/ico.0000000000000132

Cited by 15 publications

(16 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our patient had iridocorneal adhesion only in the LE and did not have anterior embryotoxon in both the eyes. Spontaneous filtering bleb formation due to corneal pathologies such as Terrien and pellucid marginal degeneration have been reported by Soong et al .,[ 2 ] Munro et al .,[ 3 ] and Toriyama et al . [ 8 ] Mechanism proposed was the extreme distortion and stretching of the peripheral cornea resulting in rupture of the Descemet's membrane and bleb formation.…”

Section: Discussionmentioning

confidence: 99%

“…Two patients with spontaneous filtering bleb without any other ocular or systemic abnormalities have been reported by Munro et al . [ 3 ] and Tatham et al . [ 10 ]…”

Section: Discussionmentioning

confidence: 99%

“…Spontaneous subconjunctival filtering bleb is a rare occurrence and has been observed with ocular or systemic abnormalities such as Axenfeld syndrome,[ 1 ] Terrien marginal degeneration,[ 2 3 ] familial craniofacial dysmorphism,[ 4 5 ] scleritis,[ 6 ] and connective tissue diseases. [ 7 ] To the best of our knowledge, only few cases have been reported till date, and we report a 26-year-old patient with bilateral spontaneous filtering bleb.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Bilateral idiopathic spontaneous filtering bleb with ectopia lentis: A case report and review of literature

Chandran

Khairnar

Aboobacker

et al. 2018

Indian J Ophthalmol

View full text Add to dashboard Cite

A 26-year-old male presented with superior filtering bleb with scleral thinning, dislocated lens, and hypotony in both the eyes. His cornea was normal without any sign of ectasia, and there was no history of recurrent redness, trauma, or surgery in either eye. Anterior segment optical coherence tomography did not reveal communicating fistula between the anterior chamber and subconjunctival space. Physical examination and blood investigations did not reveal any systemic association. He was diagnosed to have spontaneous filtering bleb, which is a rare condition observed with ocular or systemic abnormalities.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Two patients with spontaneous filtering bleb without any other ocular or systemic abnormalities have been reported by Munro et al . [ 3 ] and Tatham et al . [ 10 ]…”

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Bilateral idiopathic spontaneous filtering bleb with ectopia lentis: A case report and review of literature

Chandran

Khairnar

Aboobacker

et al. 2018

Indian J Ophthalmol

View full text Add to dashboard Cite

show abstract

“…They are reported in association with ocular abnormalities like Axenfeld syndrome, Terrien's marginal degeneration, microspherophakia, ectopia lentis, scleritis, and pellucid marginal corneal degeneration. 2 , 3 , 4 , 5 , 6 , 7 , 8 There are reports of spontaneous filtering blebs in systemic conditions like scleroderma and Traboulsi syndrome. 9 , 10 , 11 , 12 In this study, we present a case with mild craniofacial dysmorphism, microspherophakia, and bilateral spontaneous filtering blebs.…”

Section: Introductionmentioning

confidence: 99%

Bilateral spontaneous filtering blebs

Mohammadi¹,

Tabatabaei²

2020

American Journal of Ophthalmology Case Reports

View full text Add to dashboard Cite

Purpose To report a case of bilateral spontaneous filtering bleb, scleral thinning, microspherophakia, and mild craniofacial dysmorphism. Observations An 18-year-old girl was referred to our clinic for evaluation of bilateral spontaneous filtering blebs. Her corrected distance visual acuity (CDVA) was 20/400 in the right eye (RE) and 20/100 in the left eye (LE). She had superior scleral thinning, multicystic filtering bleb, and microspherophakia bilaterally. The IOP was 9 mmHg in the RE and 8 mmHg in the LE. A mild craniofacial dysmorphism including downward slanting of palpebral fissures and malar hypoplasia was present. There was no sign of corneal ectasia in tomography. Anterior segment optical coherence tomography revealed the filtering blebs as subconjunctival low reflective fluid-filled spaces. Due to severe scleral thinning un the RE we performed a tectonic scleral patch graft. 6 months after surgery the depth of the anterior chamber increased and CDVA improved. Conclusion and importance This case indicated that the formation of spontaneous filtering blebs may occur in a syndromic condition. In any case with this symptom, special attention should be paid to craniofacial features, sclera, crystalline lens, and IOP. Tectonic scleral patch graft could be a valuable option in selected patients.

show abstract

“…Spontaneous filtering blebs are an uncommon entity, the appearance of which may be favored in patients with previous history of penetrating trauma 1 or penetrating ocular procedures, such as cataract surgery or scleral fixated intraocular lens (IOL) implantation. 2 They have also been described in cases without history of trauma or surgery but with ocular thinning abnormalities, such as Terrien’s marginal degeneration, 3 pellucid marginal degeneration, 4 Axenfeld syndrome, 5 scleritis, 6 microspherophakia, 7 systemic disorders like scleroderma, 8 and craniofacial dysmorphism, 9 or other connective tissue diseases with thin sclerae, such as high myopia. However, in some cases, the etiology cannot be determined.…”

Section: Introductionmentioning

confidence: 99%

Unilateral spontaneous filtering bleb dissecting into the cornea in a patient with high myopia

Sanjuán

Salvador-Culla

Canut

et al. 2019

European Journal of Ophthalmology

View full text Add to dashboard Cite

Purpose: To report a case of a unilateral spontaneous filtering bleb dissecting into the cornea in a patient with high myopia. Clinical case: A 33-year-old woman with high myopia (–18 D) presented with discomfort in the left eye. Ocular history included pars plana vitrectomy and cataract extraction and posterior chamber intraocular lens implantation in the left eye. Best-corrected visual acuity was 0.65 and intraocular pressure was 20 mmHg. Slit-lamp examination showed a filtering bleb in the upper-temporal quadrant, which extended and dissected the proximal cornea without affecting the visual axis. The morphology and content of the bleb was studied with anterior segment optical coherence tomography, which ruled out a corneal-scleral fistulization into the subconjunctival space. The spontaneous filtering bleb was resected surgically. Due to her high myopia, two strips of fascia lata were used to strengthen the area. In the postoperative period, a complete resection of the bleb was confirmed, without apparent leaking points and with a well-vascularized conjunctiva. No complications were noted. The patient maintained the same best-corrected visual acuity and intraocular pressure than before surgery. Conclusion: The formation of a spontaneous filtering bleb is a rare entity in patients with high myopia, whose risk increases due to their thinned sclerae. The risk is even greater if they have undergone ocular surgeries. Resection of the filtering bleb in our case halted the progression of the corneal dissection, therefore respecting the transparency of the visual axis and preserving visual acuity.

show abstract

Two Cases of Spontaneous Filtering Blebs, One Idiopathic and One Associated With Terrien Marginal Degeneration

Cited by 15 publications

References 8 publications

Bilateral idiopathic spontaneous filtering bleb with ectopia lentis: A case report and review of literature

Bilateral idiopathic spontaneous filtering bleb with ectopia lentis: A case report and review of literature

Bilateral spontaneous filtering blebs

Unilateral spontaneous filtering bleb dissecting into the cornea in a patient with high myopia

Contact Info

Product

Resources

About