“…Therefore, Klemm used hand-made cement beads to increase the surface area and achieved good results [ 6 ]. Recently, treatment targets have been expanded to include osteomyelitis, postarthroplasty infections, and diabetic foot infections [ [7] , [8] , [9] , [10] , [11] ]. In the past, antibiotic-loaded acrylic cement has been produced in a variety of ways, such as by stringing together spherical beads using nonabsorbable thread or soft steel wire or by wrapping them around the steel wire.…”