Two dimensional and Doppler echocardiographic evaluation of patients presenting at Obafemi Awolowo University Teaching Hospitals Complex&amp;nbsp;Ile Ife Nigeria a prospective study of 2501 subjects

Adebayo, Rasaaq A; Akinwusi, PO; Balogun, Michael O.; Akintomide, Anthony Olubunmi; Adeyeye, Victor O.; Abiodun, Olugbenga O.; Bisiriyu, Luqman A.; Ogunyemi, Suraj A; Ajayi, Ebenezer Adekunle; Ajayi, Olufemi E.; Oyedeji, Adebayo Tolulope

doi:10.2147/ijgm.s43614

Cited by 19 publications

(24 citation statements)

References 18 publications

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“…Of note, there was no case of RHD in our series. This finding is in keeping with previous studies suggesting a downward trend in the incidence of RHD 8,20. Another possible reason for this is the socio-economic class to which most of the subjects in the study belong to.…”

Section: Discussionsupporting

confidence: 92%

Spectrum of Echocardiography Abnormalities among 168 Consecutive Referrals to an Urban Private Hospital in South-Western Nigeria

Oyedeji

Akintunde

Owojori

et al. 2014

Clin Med Insights Cardiol

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Trans-thoracic echocardiography (TTE) is an important non-invasive cardiac examination that provides structural and functional information. It is useful in the diagnosis of cardiac diseases and often guides the management and follow-up of patients with cardiovascular diseases (CVD).The study aimed to present an audit of the echocardiograms performed in an urban private hospital over a two-year period in order to define the pattern of cardiac diseases in our center. Echocardiogram reports of 168 consecutive patients performed between May 2011 and April 2013 at an organized private sector hospital in Lagos, south-west Nigeria were reviewed. Studies were performed with a Toshiba Nemio XG ultrasound machine. The data obtained were analyzed for mean age, sex, clinical indications, and echocardiographic diagnosis in the study subjects.A total of 168 echocardiography reports were examined, comprising of 92 males (54.8%) and 76 females (45.2%). The age range of the subjects was 10–76 years (mean 42.5 ± 12.1 years). The commonest indication for echocardiography was systemic hypertension and hypertension related causes (38.1%), followed by abnormal resting electrocardiogram (14.9%). Routine annual medical screening was the next most common indication, representing 13.1% of the indications for echocardiography. The other indications are as presented in Table 1. The echocardiogram was normal in 64.3% of the subjects. The commonest abnormality detected was hypertensive heart disease (HHD); accounting for 9.6% of the subjects studied. Isolated atrial enlargement (left, right, or bi-atrial) was the next most common abnormality accounting for 6% of the echocardiographic diagnosis. Pulmonary hypertension was the next most common diagnosis accounting for 4.8% of our findings. The other echocardiographic diagnoses are as listed in Table 2.Hypertension represents the commonest indication for echocardiography. Normal echocardiogram was the commonest echocardiographic finding while HHD was the commonest echocardiographic abnormality. The prevalence of ischemic heart disease by echocardiography was 2.4%. There was no case of rheumatic heart disease (RHD). The prevalence of hypertrophic cardiomyopathy (HCM) was 1.2%. Ease of access to echocardiography may influence the findings in an echocardiographic audit and policy makers should incorporate appropriateness criteria into their guidelines for reimbursement.

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Section: Discussionsupporting

confidence: 92%

Spectrum of Echocardiography Abnormalities among 168 Consecutive Referrals to an Urban Private Hospital in South-Western Nigeria

Oyedeji

Akintunde

Owojori

et al. 2014

Clin Med Insights Cardiol

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“… 6 However, the mean age aligned with the findings in Ile-Ife (Southwestern Nigeria) and Enugu (Southeastern Nigeria). 7 8 …”

Section: Discussionmentioning

confidence: 99%

“…The finding of hypertensive heart disease being the most common heart disease agreed with previous publications from Nigeria. 6 7 8 Hypertensive heart disease is a complication of hypertension, which is the most prevalent cardiovascular disease in Sub-Saharan Africa. 9…”

Section: Discussionmentioning

confidence: 99%

Pattern of heart diseases in gombe and environs: A 5-year echocardiographic review

et al. 2020

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Background: Heart disease in the developing world is mainly due to nonischemic causes-hypertensive heart disease, valvular and myocardial damage from rheumatic fever, and heart muscle diseases caused by certain infectious agents, for example, cardiomyopathy from HIV infection. Peripartum cardiomyopathy is also a well-recognized cause of heart disease in developing countries. However, there is evidence of epidemiological transition toward the increasing prevalence of atherosclerotic cardiovascular disease in Sub-Saharan Africa largely because of the increasing prevalence of traditional risk factors, such as hypertension, diabetes mellitus, dyslipidemia, obesity, and cigarette smoking. Aim: The aim of this study was to determine the pattern of heart diseases among patients undergoing transthoracic echocardiographic evaluation between February 2012 and February 2017 at the Cardiology Unit of the Department of Medicine, Federal Teaching Hospital, Gombe, Gombe State. Materials and Methods: Echocardiographic data of patients from February 2012 to February 2017 were retrieved. A total of 2265 patient records were analyzed. All patients had standard resting transthoracic echocardiography including Doppler modalities where appropriate. Descriptive statistics were used in assessing the distribution of different heart diseases. Results: The age range of the 2265 patients was 14–89 years, with a mean age of 47.3 ± 20.1 years and a female preponderance (58%). The most common heart disease among these patients was hypertensive heart disease (41.8%) followed by cardiomyopathies (15.4%). Ischemic heart disease remains rare (0.7%) probably due to the investigative modality used in this study (resting transthoracic echocardiography). Conclusion: Hypertensive heart disease remains the most common heart disease among men and women in Gombe and its environs. Cardiomyopathies, although rare in certain regions of Nigeria, are quite common in Northeast Nigeria.

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“… 1 – 3 There are some common underlying causes of heart failure in our environment, and MCTD is a rare cause of heart failure with unknown reports in Africa. 4 We hereby present a case of MCTD complicated by heart failure with the associated management challenges in our resource-limited economic environment. The way we overcame the challenges may be useful for others in similar circumstances in addition to adding information to the local and international databases about MCTD.…”

Section: Introductionmentioning

confidence: 99%

Mixed connective tissue disease complicated by heart failure in Ile-Ife, Nigeria: management challenges in a resource-limited economy

Adewuya¹,

Adebayo²,

Ajibade³

et al. 2018

IMCRJ

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BackgroundMixed connective tissue disease (MCTD; also known as Sharp’s syndrome) is a rare autoimmune inflammatory disorder characterized by high titer of U1 ribonucleoprotein (U1RNP) antibody and clinical and serological overlap of systemic lupus erythematosus, systemic sclerosis, and polymyositis. The diagnosis is based on clinical and serological factors in criteria such as Alarcon-Segovia, Khan, Kusakawa, and Sharps. Cardiac disease can be a complication of connective tissue disease (CTD). There are few reports in Africa.AimsTo present MCTD as underlying cause of heart failure with reduced ejection fraction and highlight challenges of investigations and treatment.ObjectivesTo highlight the first case in our center and discuss the cardiac, respiratory, and rheumatologic management.Patient and methodsWe present a 52-year-old woman with 3 weeks history of productive cough with whitish sputum, severe dyspnea, orthopnea, paroxysmal nocturnal dyspnea, right sided abdominal pain, leg swellings, a one year history of recurrent fever, Raynaud’s phenomenon, small joint swellings and deformities with pain in both hands.ResultsOn examination there was microstomia, tethered forehead and lower eyelid skin, tender swelling of the interphalangeal joints and arthritis mutilans. Laboratory findings showed estimated glomerular filtration rate <60 mL/kg/min/1.73 m2, U1RNP antibody levels were eight times upper limit of normal, elevated rheumatoid factor, speckled antinuclear antibody pattern, negative anticentromere antibody, anti Scl-70 and anticyclic citrullinated peptide. Chest X-ray/CT revealed pulmonary fibrosis. Echocardiography findings showed reduced ejection fraction of 40%, elevated pulmonary arterial pressure at rest of 60.16 mmHg. The patient showed improvement on antifailure drugs, but prednisolone was stopped for sudden reversal of previously controlled stage 2 hypertension (HTN), and the patient was discharged in a stable condition. Difficulties ensued in obtaining prompt definite results due to the unavailability of serologic tests in the hospital, and the tests were done outside the state and country.ConclusionIdentifying MCTD is critical, especially in patients requiring steroids that may worsen systemic HTN and heart failure. There is a need to have definitive investigative facilities for such patients in hospitals.

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Two dimensional and Doppler echocardiographic evaluation of patients presenting at Obafemi Awolowo University Teaching Hospitals Complex Ile Ife Nigeria a prospective study of 2501 subjects

Cited by 19 publications

References 18 publications

Spectrum of Echocardiography Abnormalities among 168 Consecutive Referrals to an Urban Private Hospital in South-Western Nigeria

Spectrum of Echocardiography Abnormalities among 168 Consecutive Referrals to an Urban Private Hospital in South-Western Nigeria

Pattern of heart diseases in gombe and environs: A 5-year echocardiographic review

Mixed connective tissue disease complicated by heart failure in Ile-Ife, Nigeria: management challenges in a resource-limited economy

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