Two-Dimensional Echocardiographic Right Ventricular Size and Systolic Function Measurements Stratified by Sex, Age, and Ethnicity: Results of the World Alliance of Societies of Echocardiography Study

Addetia, Karima; Miyoshi, Tatsuya; Citro, Rodolfo; Daimon, Masao; Fajardo, Pedro Gutiérrez; Kasliwal, Ravi R; Kirkpatrick, James N.; Monaghan, Mark; Muraru, Denisa; Ogunyankin, Kofo O.; Park, Seung Woo; Ronderos, Ricardo; Sadeghpour, Anita; Scalia, G.; Takeuchi, Masaaki; Tsang, Wendy; Tucay, Edwin S.; Rodrigues, Ana Clara Tude; Amuthan, Vivekanandan; Zhang, Yun; Schreckenberg, Marcus; Mor‐Avi, Victor; Asch, Federico M.; Lang, Roberto M.; Investigators, Wase

doi:10.1016/j.echo.2021.06.013

Cited by 69 publications

(69 citation statements)

References 24 publications

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“…RV function is difficult to evaluate in echocardiography because of its complex geometry. Addetia K, et al [ 13 ] used RV systolic parameters, such as basal and mid-RV dimensions, length, TAPSE, tissue Doppler S′ velocity, and RV longitudinal strain in normal subjects, and found that RV strain was believed to better represent RV systolic function than longitudinal measurements. Previous studies mainly focused on some diseases may damage RV functions directly, such as pulmonary arteries hypertension [ 14 , 15 ], atrial septal defect [ 16 ], tetralogy of Fallot [ 17 , 18 ], severe tricuspid regurgitation [ 19 ], and so on.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of right ventricular systolic and diastolic dysfunctions in patients with type 2 diabetes mellitus with poor glycemic control by layer specific global longitudinal strain and strain rate

Huang

Fan

et al. 2022

Diabetol Metab Syndr

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Background In order to evaluate right ventricular (RV) systolic and diastolic dysfunctions in patients with type 2 diabetes mellitus (T2DM) with poor glycemic control by layer specific global longitudinal strain (GLS) and strain rate (GLSr). Methods 68 T2DM patients and 66 normal controls were enrolled for the present study. RV layer specific GLS (GLSEpi, GLSMid and GLSEndo represent the epimyocardial, middle layer and endomyocardial strains, respectively) and GLSr (GLSr-S, GLSr-E and GLSr-A represent the systole, early-diastole and late-diastole strain rate) were calculated by averaging each of the three regional peak systolic strains and strain rates along the entire RV free-wall (RVFW), entire RV free-wall and septal wall (RVFSW) on RV-focused view. Results The absolute values of RV layer specific GLS (GLSEpi, GLSMid and GLSEndo) in RVFW in T2DM patients were significantly lower than normal controls (P < 0.01), while GLSr-A was significantly larger than normal controls (P < 0.001). The absolute values of RV layer specific GLS (GLSEpi and GLSMid) in RVFSW in T2DM patients were significantly lower than normal controls (P < 0.05), while GLSr-A was significantly larger than normal controls (P < 0.001). HbA1c were poor negatived correlated with GLSEpi in RVFW and RVFSW in T2DM patients (P < 0.05). ROC analysis showed that RV layer specific GLS and GLSr-A had a high diagnostic efficacy in T2DM patients, and GLSr-A in RVFSW have the best diagnostic value in RV diastolic function in T2DM patients (AUC: 0.773). Conclusion From the research, we found that layer specific GLS and GLSr could detect the RV myocardial dysfunctions and confirmed that the impaired RV systolic and diastole functions in T2DM patients with poor glycemic control. GLSr-A in RVFSW had the best diagnostic value in evaluating RV diastolic function in T2DM patients.

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Section: Discussionmentioning

confidence: 99%

Evaluation of right ventricular systolic and diastolic dysfunctions in patients with type 2 diabetes mellitus with poor glycemic control by layer specific global longitudinal strain and strain rate

Huang

Fan

et al. 2022

Diabetol Metab Syndr

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“…We observed increased RV/LV ratio and decreased LV basal diameter in our intermediate-risk PE cohort compared to the normal reference range, and significant measurement differences between those with clinical deterioration and those without [ 16 , 17 ]. Decreased RV systolic function represents a more advanced pathophysiological stage of PE than having RV dilatation alone.…”

Section: Discussionmentioning

confidence: 83%

Intermediate-risk pulmonary embolism: echocardiography predictors of clinical deterioration

et al. 2022

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Background We determine the predictive value of transthoracic echocardiographic (TTE) metrics for clinical deterioration within 5 days in adults with intermediate-risk pulmonary embolism (PE). Methods This was a prospective observational study of intermediate-risk PE patients. To determine associations of TTE and clinical predictors with clinical deterioration, we used univariable analysis, Youden’s index for optimal thresholds, and multivariable analyses to report odds ratios (ORs) or area under the curve (AUC). Results Of 306 intermediate-risk PE patients, 115 (37.6%) experienced clinical deterioration. PE patients who had clinical deterioration within 5 days had greater baseline right ventricle (RV) dilatation and worse systolic function than the group without clinical deterioration as indicated by the following: RV basal diameter 4.46 ± 0.77 versus 4.20 ± 0.77 cm; RV/LV basal width ratio 1.14 ± 0.29 versus 1.02 ± 0.24; tricuspid annular plane systolic excursion (TAPSE) 1.56 ± 0.55 versus 1.80 ± 0.52 cm; and RV systolic excursion velocity 10.40 ± 3.58 versus 12.1 ± 12.5 cm/s, respectively. Optimal thresholds for predicting clinical deterioration were: RV basal width 3.9 cm (OR 2.85 [1.64, 4.97]), RV-to-left ventricle (RV/LV) ratio 1.08 (OR 3.32 [2.07, 5.33]), TAPSE 1.98 cm (OR 3.3 [2.06, 5.3]), systolic excursion velocity 10.10 cm/s (OR 2.85 [1.75, 4.63]), and natriuretic peptide 190 pg/mL (OR 2.89 [1.81, 4.62]). Significant independent predictors were: transient hypotension 6.1 (2.2, 18.9), highest heart rate 1.02 (1.00, 1.03), highest respiratory rate 1.02 (1.00, 1.04), and RV/LV ratio 1.29 (1.14, 1.47). By logistic regression and random forest analyses, AUCs were 0.80 (0.73, 0.87) and 0.78 (0.70, 0.85), respectively. Conclusions Basal RV, RV/LV ratio, and RV systolic function measurements were significantly different between intermediate-risk PE patients grouped by subsequent clinical deterioration.

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“…Parasternal short-axis midventricular level showing an improvement in LV systolic D shape compared with the previous echocardiography. Video 6 Follow-up serial echocardiogram, apical four-chamber RV-focused view for RV longitudinal strain assessment after 6 months of pulmonary vasodilator treatment showing an RVFWLS of –27% (normal value, –37.2% to –20.8%) 1 and an RV postsystolic strain pattern type I showing a downward shift of the curve after peak systolic strain toward the baseline, followed by end-diastolic straight curve. …”

Section: Supplementary Datamentioning

confidence: 99%

“…Video 2 Pretreatment echocardiogram, parasternal short-axis midventricular level showing an LV systolic D shape suggesting RV pressure overload. Video 3 Pretreatment echocardiogram, apical four-chamber RV-focused view for RV longitudinal strain assessment showing an RVFWLS of –19.4% (normal value, –37.2% to –20.8%) 1 and an RV postsystolic strain pattern type II showing a steady negative plateau from peak systolic strain through early diastole, followed by a positive downward shift toward baseline. Video 4 Follow-up serial echocardiogram after 6 months of pulmonary vasodilator treatment.…”

Section: Supplementary Datamentioning

confidence: 99%

“… Pretreatment echocardiogram, apical four-chamber RV-focused view for RV longitudinal strain assessment showing an RVFWLS of –19.4% (normal value, –37.2% to –20.8%) 1 and an RV postsystolic strain pattern type II showing a steady negative plateau from peak systolic strain through early diastole, followed by a positive downward shift toward baseline. …”

Section: Supplementary Datamentioning

confidence: 99%

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Right Ventricular Postsystolic Strain Curve Morphology before and after Vasodilator Treatment in Idiopathic Pulmonary Arterial Hypertension

Rodríguez-Pérez

Bos

Podzamczer

et al. 2022

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Two-Dimensional Echocardiographic Right Ventricular Size and Systolic Function Measurements Stratified by Sex, Age, and Ethnicity: Results of the World Alliance of Societies of Echocardiography Study

Cited by 69 publications

References 24 publications

Evaluation of right ventricular systolic and diastolic dysfunctions in patients with type 2 diabetes mellitus with poor glycemic control by layer specific global longitudinal strain and strain rate

Evaluation of right ventricular systolic and diastolic dysfunctions in patients with type 2 diabetes mellitus with poor glycemic control by layer specific global longitudinal strain and strain rate

Intermediate-risk pulmonary embolism: echocardiography predictors of clinical deterioration

Right Ventricular Postsystolic Strain Curve Morphology before and after Vasodilator Treatment in Idiopathic Pulmonary Arterial Hypertension

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