Two-dimensional NbS2 nanosheets with hyperthermia for killing bacteria to promote infected wound healing

Xu, Dong-Qian; He, Xiaojun; Obeng, Enoch; Ye, Zhangyan; Shen, Jianliang; Ding, Xi

doi:10.1016/j.matdes.2022.111124

Cited by 6 publications

(3 citation statements)

References 41 publications

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“…The silanol group in HMONs can form hydrogen bonds with water, improving the solubility and dispersibility The temperature of most PTAs prepared using traditional methods is uncontrollable, and the temperature may be too high during treatment, resulting in irreversible thermal damage to healthy tissues [69][70][71][72]. At present, the commonly used solution is to change the experimental conditions, such as the light power density and the concentration of PTAs [73], but the immediacy of this method is relatively poor, and heat accumulation may occur and even cause serious burns and secondary infections. Therefore, it is necessary to develop a PTT platform that can accurately and quickly adjust the temperature.…”

Section: Conjugated Small Moleculesmentioning

confidence: 99%

Recent Progress of Photothermal Therapy Based on Conjugated Nanomaterials in Combating Microbial Infections

Zhao

Wang

et al. 2023

Nanomaterials

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Photothermal therapy has the advantages of non-invasiveness, low toxicity, simple operation, a broad spectrum of antibacterial ability, and non-proneness to developing drug resistance, which provide it with irreplaceable superiority in fighting against microbial infection. The effect of photothermal therapy is closely related to the choice of photothermal agent. Conjugated nanomaterials are potential candidates for photothermal agents because of their easy modification, excellent photothermal conversion efficiency, good photostability, and biodegradability. In this paper, the application of photothermal agents based on conjugated nanomaterials in photothermal antimicrobial treatment is reviewed, including conjugated small molecules, conjugated oligomers, conjugated polymers, and pseudo-conjugated polymers. At the same time, the application of conjugated nanomaterials in the combination of photothermal therapy (PTT) and photodynamic therapy (PDT) is briefly introduced. Finally, the research status, limitations, and prospects of photothermal therapy using conjugated nanomaterials as photothermal agents are discussed.

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Section: Conjugated Small Moleculesmentioning

confidence: 99%

Recent Progress of Photothermal Therapy Based on Conjugated Nanomaterials in Combating Microbial Infections

Zhao

Wang

et al. 2023

Nanomaterials

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“…[5,6,8,9] Therefore, novel therapeutic strategies in treating of skin abscesses are urgently required. [6,7,[10][11][12][13][14][15] To address these issues, hydrogels, [5,16] nanostructures, [12,[17][18][19][20][21][22][23][24][25] and microneedle patches [26,27] have been developed. Kaplan et.…”

Section: Introductionmentioning

confidence: 99%

Copper‐Cysteine Nanostructures for Synergetic Photothermal Therapy and Chemodynamic Therapy of Bacterial Skin Abscesses

Bagheri,

Bochani,

Seyedhamzeh

et al. 2024

Advanced Therapeutics

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Skin lesions, including skin bacterial abscesses, have become one of the most important health challenges and usually need systemic high‐dose antibiotics. Therefore, it is of particular importance to develop novel approaches for treating this ever‐growing challenge to human health. To address this challenge, herein a copper nanostructure is developed giving combined photothermal and chemodynamic therapies for focal infection treatment. The Cu‐based nanostructures with intrinsic catalytic properties are prepared by D‐L or L cysteine (Cys) as ligand and copper ions. It is shown that the multifunctional copper‐Cys (Cu‐Cys) nanostructures can produce reactive oxygen species (ROS) and they exhibit near infrared (NIR)‐enhanced catalytic activities to improve ROS production for highly efficient eradication of bacteria. Moreover, the results proved O2 evolution property of the Cu‐Cys nanoparticles (NPs). The nanostructures show shape‐dependent antibacterial activity where DL‐Cu‐Cys NPs show higher bactericidal performance than L‐Cu‐Cys NPs. In vitro results demonstrate that 2.5 and 1.25 µg mL−1 of DL‐Cu‐Cys NPs is enough to achieve rapid killing of Escherichia coli (E. coli) or Staphylococcus aureus (S. aureus) respectively under 808 nm light irradiation in 10 min. This work introduces a unique photoactive nanoagent to efficiently treat subcutaneous abscess by combining NIR light‐triggered photothermal effect and catalytic generation of ROS without using any antibiotic.

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“…In addition to research and development of molecular drugs and antibiotics, 3,5 sustainable efforts have been devoted to the design and fabrication of antibacterial nanomaterials. Recently, several antibacterial nanomaterials, such as metal nanomaterials, 6,7 matrix composites, 8 transition metal dichalcogenides, 9,10 and carbon nanomaterials, 11 have been fabricated as effective antimicrobial tools. However, current new antibacterial strategies have not been able to achieve a breakthrough, likely due to the need to combine excellent antibacterial ability with an understanding of the resistance mechanisms in a cost-effective manner.…”

Section: Introductionmentioning

confidence: 99%

Quaternized carbon dots with enhanced antimicrobial ability towards Gram-negative bacteria for the treatment of acute peritonitis caused by E. coli

Zhang

Hao

et al. 2023

J. Mater. Chem. B

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Two-dimensional NbS2 nanosheets with hyperthermia for killing bacteria to promote infected wound healing

Cited by 6 publications

References 41 publications

Recent Progress of Photothermal Therapy Based on Conjugated Nanomaterials in Combating Microbial Infections

Recent Progress of Photothermal Therapy Based on Conjugated Nanomaterials in Combating Microbial Infections

Copper‐Cysteine Nanostructures for Synergetic Photothermal Therapy and Chemodynamic Therapy of Bacterial Skin Abscesses

Quaternized carbon dots with enhanced antimicrobial ability towards Gram-negative bacteria for the treatment of acute peritonitis caused by E. coli

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