Two New C19‐Diterpenoid Alkaloids from Delphinium shawurense

Ablajan, Nurfida; Xue, Wenxiang; Zhao, Jiaheng; Abdubakiev, Sardorbek; Begmatov, Nurmirza; Sagdullaev, Shamansur S.; Zhao, Bo; Aisa, Haji Akber

doi:10.1002/cbdv.202200936

Cited by 2 publications

(2 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Lycoctonine-type C19-DAs are oxidized at C-7 and C-8. Compounds 114-153 are all novel members of the lycoctonine-type C19-DAs, with 38 compounds derived from Delphinium and only 2 from Aconitum [62][63][64][65][66][67][68]. The plant sources are shown in Table 5.…”

Section: C18-dasmentioning

confidence: 99%

See 1 more Smart Citation

Exploring the Biomedical Potential of Terpenoid Alkaloids: Sources, Structures, and Activities

Wang,

Xin,

Sun

et al. 2024

Molecules

View full text Add to dashboard Cite

Terpenoid alkaloids are recognized as a class of compounds with limited numbers but potent biological activities, primarily derived from plants, with a minor proportion originating from animals and microorganisms. These alkaloids are synthesized from the same prenyl unit that forms the terpene skeleton, with the nitrogen atom introduced through β-aminoethanol, ethylamine, or methylamine, leading to a range of complex and diverse structures. Based on their skeleton type, they can be categorized into monoterpenes, sesquiterpenes, diterpenes, and triterpene alkaloids. To date, 289 natural terpenoid alkaloids, excluding triterpene alkaloids, have been identified in studies published between 2019 and 2024. These compounds demonstrate a spectrum of biological activities, including anti-inflammatory, antitumor, antibacterial, analgesic, and cardioprotective effects, making them promising candidates for further development. This review provides an overview of the sources, chemical structures, and biological activities of natural terpenoid alkaloids, serving as a reference for future research and applications in this area.

show abstract

Section: C18-dasmentioning

confidence: 99%

“…Compound 117 contains a carboxyl group attached to the nitrogen. Compounds 118 and 119 are identified as a pair of regioisomers [62]. Compound 121 from Delphinium ajacis is notable for its rare hydroxyl group at C-12 [70].…”

Section: C18-dasmentioning

confidence: 99%